| Purpose: This study observed the YouguiWan Decoction for the treatment of Hashimoto’s thyroiditis(Hashimoto Thyroiditis,HT)(spleen kidney yang deficiency,phlegm and blood stasis)clinical safety and effectiveness,To provide new ideas and methods to further improve the clinical efficacy of Chinese medicine treatment of Hashimoto’s thyroiditis,Give full play to the advantages of traditional Chinese medicine.Method: This research according to follow the principle of randomized,controlled,Observation of 60 cases of hashimoto’s thyroiditis and TCM syndrome differentiation of spleen and kidney Yang deficiency,phlegm and blood stasis resistance collaterals syndrome patients.Would be consistent with the set of conditions of patients were randomly divided into treatment group and control group,30 cases in each group.The treatment group in the diet treatment,emotion,on the basis of foundation treatment,such as giving oral levothyroxine sodium;Combined oral Chinese medicine right belongs to the pill and subtract oral,sooner or later,2 times a day after a meal and a half hours warm clothing.The control group on the basis of foundation treatment,to give oral levothyroxine sodium.Three consecutive period of treatment,a total of 12 weeks every 4 weeks for a course of treatment.Main observed before and after treatment in patients with symptoms,signs,as well as the physical and chemical inspection before and after the change,Respectively before and after treatment in patients with thyroid related hormone levels,thyroid autoantibodies drop degree,degree of goiter and the change of TCM syndrome integral evaluation.And will be more test data using SPSS17.0 analysis system software,to carry on the safety and efficacy evaluation.Result: Diagnosed and included in the experiment of two groups of patients,they before treatment in ordinary materials such as age,gender,course of no statistical difference,In thyroid autoantibodies drops,the thyroid volume,the thyroid hormone levels and TCM syndrome integral baseline data also no statistics has no obvious difference,all have the comparability between groups.To pass through the treatment right pill and subtract joint levothyroxine sodium treatment of hashimoto’s thyroiditis in reducing TPO-Ab,TG-Ab,thyroid volume,improve the thyroid hormone levels and the clinical symptoms than that in control group(that is,the simple application levothyroxine sodium)has obvious advantages(P < 0.05).Its treatment effect has more advantages,and no adverse events occurred in the process of the entire study.Conclusion: Right to pill-add and subtract in improving the thyroid hormone levels and clinical symptoms,reduce the TPO Ab,TG-Ab level,narrow the thyroid volume levothyroxine sodium is obviously better than the control group,and no side effects in clinical observation.Bluff Chinese medicine treatment of hashimoto’s thyroiditis,can reduce the autoimmunity,and delay the disease,but it still remains to be further perfect.Through the clinical observation confirmed that right belongs to the pill can add and subtract for traditional Chinese medicine treatment of hashimoto’s thyroiditis with new ideas and new methods. |
