Synthesis Of Amphiphilic Oligomers With Different Groups At Their Ends And Their Morphology Control

Molecular self-assembly is ubiquitous in nature and in daily life.Membranes of living cells are formed by the self-assembly of phospholipids.Soap bubbles,which are encountered when soaps are used,originate from the self-assembly of smallmolecule surfactants.All of these molecules consist of one or more hydrophobic tails and a hydrophilic head group.To understand molecular self assembly and to explore potential applications,it motivates the researchers to investigate on molecular self-assembly principles,theories,structures and their properties.The self-assembly of small molecule amphiphiles has been studied for many decades,and various morphology has been observed in bulk and in aqueous solutions.The structures and the properties of the self-assemblies formed by amphiphiles are determined by their architectures(interplay between the hydrophilic-hydrophobic balance and geometric packing constraints)and experimental conditions,such as concentration,temperature,pH,and ionic strength.Thus under different conditions,amphiphilic molecules can form a wide variety of microstructures,including spherical,rod-like and disc-like micelles,reverse micelles,bilayer vesicles,flat bilayers,etc.in selective solution above cmc.Self-assembly of amphiphilic polymers is of great interest to scientists because the linking of two or more dissimilar polymers allows for the realization of new materials properties and useful self-assembled morphologies.In this thesis,we designed and synthesized linear amphiphilic molecules and V-shape amphiphilic molecules containing different groups and hydrophilic chains with different degrees of polymerization,and the self-assembly morphology of these target molecules was analyzed by a series of experiments.Intermolecular interactions,such as hydrophobic interactions and ?-? stacking interaction and the space constraints between the aromatic blocks et.that can be altered by adjusting the shape of the rigid rod block of the amphiphilic molecule,introducing different active centers,the degree of polymerization of the flexible block,and the cross-sectional area.Because unique structure and properties of each of the self-assemblies can be used for various applications,such as solubilization,encapsulation,delivery,etc.Therefore,understanding the solution properties and self-assembly behavior of amphiphilic molecules is important for the development of new and practical applications,This work enriches rational building units for complex and functional materials,and provides a more succinct approach for the formation of a variety of self-assembled aggregate topography.