Study On Formation Technology Of High Concentration Ozone Solution And Treatment Of Griseofulvin

As an antibiotic against fungal diseases,griseofulvin has achieved good performance in clinical applications.At the same time,it can be applied to a variety of fields such as agriculture,animal husbandry and aquaculture.Because in the production of ash lutein will produce pharmaceutical residues do not deal with the complete situation,direct discharge into the water environment,water resources caused serious pollution,and even threatened human health.In this paper,the low temperature plasma source strong ionization discharge form,oxygen ionization dissociation,the formation of a large number of high-concentration ozone gas,gray lutein effective oxidation degradation.This paper is divided into two parts,the first part is the high concentration ozone water formation technology,the second part is the ozone oxidation degradation ash lutein experimental study.The research contents and research results are as follows:(1)In this experiment,a high-concentration ozone gas was generated by strong ionization discharge,and the optimum experimental parameters of high concentration ozone water were formed by changing the factors such as ozone gas flow rate,gas-liquid ratio,internal pressure and residence time of the system.The results show that changing the input power of plasma source and the internal pressure of plasma source have an effect on increasing the concentration of ozone gas,and under the condition of single experiment,when the gas-liquid mixing mode adopts the inlet water intake mode,the gas-liquid ratio is between 0.5 and 1,and the residence time is the best experimental condition in 2-5 s.At the same time,the ozone water concentration can be increased by superimposing the number of plasma sources,and the ozone water concentration reaches 51.6 ppm.Under the condition of cyclic experiment,the optimum conditions are experimental when the oxygen gas flow rate is 4.0 L/min,the outlet pressure of gas and water mixer is 0.1 MPa,the input power is one W and the total water quantity is L,and the experimental system can run stably at this time,and the ozone water concentration can reach 40.3 ppm.(2)This experiment explored the effects of input power,residence time,solution pH,dosage,inhibitors and inorganic salt ions on the degradation efficiency of griseofulvin.The experimental results show that the degradation efficiency of griseofulvin reaches 94.7%when the input power is 125 W;the degradation rate can reach 97%when the residence time is 1 s;the initial solution pH is more neutral or alkaline.It is beneficial to the degradation of griseofulvin by ozone in water.When the pH value of the solution is 10.8,the degradation rate reaches 98%;when the dosage of ozone is 234.6 mg/min,the degradation rate of griseofulvin can reach 98%;Butanol and sodium carbonate were used as inhibitors.When the concentration of 30 mg/L sodium carbonate and tert-butanol was added,it was found that tert-butanol had a certain inhibitory effect on the dissolved ozone oxidation degradation of griseofulvin in water;the concentration was 30 mg/L inorganic salt ions have little effect on the degradation rate of griseofulvin,and the degradation rate of griseofulvin can reach 97%.