Preparation And Properties Of Antibacterial Fibers Based On The Catalytic Characteristic Of Iron Phthalocyanine

With the continuous improvement of the economic level,people's awareness of health protection has also increased,and green and efficient new antibacterial materials have emerged as the times require.At the same time,the aging society has stimulated the market demand for antibacterial medical and health materials.The current antibacterial materials are mainly antibacterial functional materials containing silver,copper,zinc and other metal ions and their oxides,which have the disadvantages of high cost,easy dissolution of metal ions and cytotoxicity.Because of the abuse of antibiotics,the resistance of bacteria is increasing,and the efficiency of traditional antibiotics is decreasing.It is is an urgent need to develop a new,efficient and low cost antibacterial material.Metal phthalocyanine is a macrocyclic metal complex similar to the porphyrin structure of the cytochrome P450 active center.It has good catalytic activity and chemical stability.It can be supported by different supports and used in various fields of catalysis.Under light conditions,metal phthalocyanine can be used as a photosensitizer in cancer photodynamic therapy(PDT),but whether it can develop non-photoresponse metal phthalocyanine antibacterial materials and its application in the field of antibacterial is more significant.Polyester fiber,as an industrially mass-produced fiber,can be applied in various fields.Polyester fiber is used to load metal phthalocyanine to improve its reusability,stability and dispersibility,and is used in the field of antibacterial.In this paper,iron phthalocyanine(FePc)was loaded on polyethylene terephthalate(PET)by spinning method to obtain iron phthalocyanine/polyester nanofibers(FePc/PET).The surface modification of the fiber by alkali treatment yielded iron phthalocyanine/polyester nanofibers(FePc/PET-T)with more active sites.The morphology of the antibacterial fiber was analyzed by a series of characterization methods including field emission scanning electron microscope(FESEM),X-ray diffraction(2D-XRD),and ultraviolet-visible absorption spectrum(UV-vis).Using S.au and E.coli as model strains to study the antibacterial properties of FePc/PET,the results show that FePc/PET-T has a 100%sterilization rate against S.au and a 95%sterilization rate against E.coli.In order to further study the fiber surface properties,through X-ray photoelectron spectroscopy(XPS),contact angle,and Zeta potential analysis,the zeta potential of the fiber surface is reduced,and the hydrophilicity is improved,which significantly improves the antibacterial performance of the fiber.In terms of mechanism analysis,the axial coordination of thiol groups in cysteine(L-cy)with FePc was used to study the catalytic antibacterial mechanism of FePc.It was found that the axial coordination of FePc is the key to catalyze the antibacterial process.This paper speculates that FePc/PET interacts with oxygen(O2)during the reaction to generate superoxide radicals(·O2-),hydrogen peroxide(H2O2),hydroxyl radicals(·OH),and peroxy radicals(·OOH)reactive oxygen free radicals,which can inhibit the reproduction of bacteria.The paper further uses polyacrylonitrile(PAN),which is more hydrophilic than PET,as the carrier.FePc is supported on the PAN by the spinning method to obtain iron phthalocyanine/polyacrylonitrile nanofibers(FePc/PAN).The surface modification of the fiber by alkali treatment resulted in iron phthalocyanine/polyacrylonitrile nanofibers(FePc/PAN-T)with more active sites.The morphology of the antibacterial fiber was analyzed using a series of characterization methods such as FESEM,2D-XRD,and UV-vis.Similarly,S.au and E.coli were used as model strains to study the antibacterial performance of FePc/PAN.The results show that FePc/PAN has 95%antibacterial activity against S.au,but has no antibacterial effect against E.coli.The surface modification of FePc/PAN by alkali treatment shows that the antibacterial efficiency of FePc/PAN-T against E.coli is 97.6%.In order to further study the fiber surface properties,XPS analysis showed that further improvement of hydrophilicity is helpful to improve the antibacterial performance.In addition,the color reaction of N,N-diethyl-p-phenylenediamine(DPD)proved that hydrogen peroxide(H2O2)was produced in the antibacterial system.The research group of this research group studied the fenton-like system of FePc/PAN nanofibers in the early stage and found that in the presence of FePc/PAN nanofibers,the hydroxyl radicals(·OH)and peroxy radicals(·OOH)formed by the decomposition of H2O2.Therefore,it is speculated that in the reaction process of the presence of H2O2,the antibacterial system can use the formed H2O2 to further generate-OH and ·OOH.This paper speculates that FePc/PAN interacts with O2 during the reaction to generate·O2-,H2O2,·OH,and ·OOH,thereby inactivating S.au and E.coli.The research in this thesis provides a new idea and method for exploring the use of catalysis to make antibacterial fibers.