Preparation Of Magnetic Metal Phthalocyanine Catalyst And Its Application In Catalytic Baeyer-Villiger Oxidation Of Cyclic Ketones

Baeyer-Villiger(B-V)oxidation is a valuable organic reaction that can directly convert ketones to the corresponding lactones or esters.However,as a traditional oxidant,organic peroxy acid has the disadvantages of high cost,low selectivity and environmental hazards,so it is gradually replaced by H2O2,which is green and environmentally friendly.But high concentrations of H2O2 also has a high risk.Although the catalytic activity of biological enzymes is high,the maintenance of biological enzyme activities requires stricter operating conditions Therefore,exploring low-cost and environmentally friendly high-efficiency catalysts and oxidants to catalyze the oxidation of cyclic ketone compounds under mild conditions in Baeyer-Villiger oxidation has become a hot research topic todayFirst,this article summarizes the background of the progress of Baeyer-Villiger reaction research.The loading of metal phthalocyanine catalysts and the research progress of magnetic particles as carriers are summarized,as well as the significance and main research content of this articleSecond,combined with the research results of our laboratory,Tetraamido Cobalt Phthalocyanine was synthesized and loaded onto chitosan-coated magnetic microspheres.The catalyst was analyzed by Fourier infrared spectroscopy,ultraviolet-visible spectrophotometer and XRD.The surface morphology of the catalyst is observed by SEM,and the magnetization performance of the catalyst is studied by VSM.According to the experimental results,the phthalocyanine was successfully loaded onto the magnetic microspheresThird,the reaction condition of oxidizing cyclohexanone with CoTaPc-Fe3O4/CTO was studied,and the influencing factors of the catalytic system on the oxidation of cyclohexanone were explored.By screening the variables of temperature,reaction time,solvent and molar ratio,the best reaction conditions were obtained.Optimized reaction conditions:substrate 0.025mol,benzaldehyde 0.05mol,CoTaPc-Fe3O4/CTO 0.12g,1,2-dichloroethane 25 mL,12 hours.By these conditions,cyclohexanone can be well converted and a higher yield of ?-caprolactone can be obtainedFourth,through Raman spectroscopy and control experiments,the mechanism of CoTaPc-Fe3O4/CTO catalyzed the Baeyer-Villiger oxidation was studied CoTaPc-Fe3O4/CTO can promote the Baeyer-Villiger oxidation through accelerating the conversion process of benzaldehyde to peroxybenzoic acid.