Design And Experimental Study Of A New Wound Closure Device

BackgroundWar traumatic bleeding is the leading cause of death in the wounded.Massive bleeding can increase the incidence and mortality of hypotension,lack of coagulation factors and multiple organ failure.About 18%of war trauma deaths can be prevented by effective hemostasis.The 2016 edition of TCCC(Tactical Combat Casualty Care)guidelines put hemostasis at the top of the battle trauma treatment.Effective hemostasis plays an important role in reducing the blood transfusion pressure and improving the survival rate of the injured in peacetime and war.Currently equipped hemostatic dressings are commonly used in wounds that can cause vascular damage in the pressurized region that are not suitable for tourniquet,such as groin,neck or underarm wounds.The hemostasis dressing can not effectively pressurize the above parts,it will also cause a large amount of blood loss,even trained medical personnel can not stop bleeding quickly in a short period of time.Therefore,pre-hospital first aid requires a rapid and effective hemostatic technique.Traditional hemostasis dressings,such as gauze bandages,have a better effect on bleeding in areas that can be directly compressed,but are not sufficient for bleeding in areas that cannot be effectively compressed,and the armpit in these uncontrollable bleeding.Neck and groin bleeding accounted for 20%.In order to meet the requirements of wound closure and hemostasis in first aid,a new wound closure device should be designed.ObjectiveA new type of wound closure device is designed,which is small in volume,strong in strength and convenient to use,and can stop bleeding effectively at the junction of limbs and torso.The rationality and effectiveness of the device are verified,and the advantages and disadvantages of the device in wound closure are analyzed,and the advantages and disadvantages of the device in wound closure are analyzed.The invention provides a new type of device for self-rescue and mutual rescue.Methods(1)The model of rapid wound closure device is designed by solidworks software,which meets the requirements of convenient use,easy grasping,easy disassembly and reusable use.(2)According to mechanics,engineering and medical principles,a new type of wound closure device was designed by finite element analysis and mechanical test.Samples of closure device were made by 3D printing technique and its structure was verified.(3)A new wound closure device,which was printed by 3D printing technique,was compared with the traditional gauze bandaging in vitro.The general shape of closing wound was closed and the closeness of wound was verified on the skin in vitro.Collect data and make statistical analysis.(4)The animal experiment of rapid wound closure device was carried out to verify the wound closure and hemostatic performance.The physiological parameters of the experimental animals were collected and statistically analyzed to compare the statistical differences between the two methods of hemostasis.Results(1)The mechanical structure of a 3 D printed wound closure device meets the requirements of wound closure.Easy to use,easy to grasp,ergonomic.After closure,the skin margin of the wound was turned over,and the closure device had no obvious damage to the skin.(2)The maximum value of the wound closure device for the horizontal tensile force test was f=26.27 N.The average of 10 times of vertical tensile test is=55.7 N.The weight of 5 kg can be lifted.The average force of sewn needle piercing the skin is 4.5 NS,which is greater than that of 4.38 N when the wound closure device is closed and locked.Therefore,the tip of the wound closure device does not damage the skin when the wound closure device is used to close the wound.(3)At the end of the experiment,all the animals in group a survived,the average survival time was more than 180 min.The average survival time of group B was 129 minutes.The amount of bleeding in group A was(488.78±40.57)g,group B was(809.84±127.82)g,and the difference was statistically significant(P<0.047).There was no significant difference in physiological parameters such as heart rate,blood pressure and oxygen saturation between the two groups.A new type of wound closure device is used to close the wound,which is superior to the normal gauze.ConclusionsThe new type of wound closure device is designed to meet the requirements of rapid wound closure and hemostasis.It solves the problem of blood clogging and hemostasis of bleeding at the junction of limbs and torso,and achieves the purpose of fast wound closure and hemostasis,and has a significant advantage over the common gauze compression bandaging.