With the increase of the aging population and people's increasing concern for health,the demand for drugs in China is increasing,which leads to the increasing importance of cold chain logistics and distribution of drugs.However,China's pharmaceutical cold chain logistics starts late,the distribution path is unreasonable,and the distribution cost increases year by year,which seriously threatens the further development of the pharmaceutical cold chain logistics industry in China.According to the current situation of cold chain logistics development in China,scholars at home and abroad have made a reasonable and efficient distribution path from reducing carbon emissions,reducing costs,increasing the circulation of pharmaceutical products and so on,which is of great theoretical significance and practical value to study the optimization of distribution path of pharmaceutical cold chain logisticsWith the increase of the aging population and people's increasing concern for health,the demand for drugs in China is increasing.This paper takes a pharmaceutical company as the research object,discusses the problems existing in the company's drug logistics and distribution,uses the logistics and distribution path optimization model and improved genetic algorithm and saving method to solve the model,and finally puts forward the logistics and distribution path Optimized solution.First of all,from the general direction and background of cold chain logistics of medicine in China and the research status at home and abroad,this paper expounds the research significance,research content and research direction.This paper discusses the definition and characteristics of drug cold chain logistics,as well as the definition and components of vehicle route optimization,and the algorithm comparison of vehicle route optimization,and determines the algorithm of this paper.Then,the paper analyzes the current situation of cold chain logistics of a pharmaceutical company from two aspects of basic operation and distribution network,summarizes the problems existing in cold chain logistics distribution of a pharmaceutical company,and concludes that the main reason for the problems in cold chain logistics distribution path is that the logistics distribution path is unreasonable.Then,the paper analyzes the current situation of cold chain logistics of a pharmaceutical enterprise from two aspects of basic operation and distribution network,summarizes the actual situation of cold chain logistics distribution of a pharmaceutical enterprise,and concludes that the main reason for the problems in the cold chain logistics distribution path of the enterprise is the unreasonable logistics distribution path.Then,the problem of cold chain logistics of a pharmaceutical enterprise is analyzed,and the objective of logistics path optimization is determined.Then,the model hypothesis and constraint conditions are determined,and the objective function and constraint conditions are formulated.The logistics distribution path optimization model with time window constraints and the coldchain logistics distribution path optimization model are constructed respectively for the hospital,pharmacy and clinic.The hospital cold chain logistics distribution path optimization model has time window constraints,so the improved saving method is used to solve it;for the cold chain logistics distribution path optimization model constructed by clinics and pharmacies,the improved genetic algorithm is used to solve it,which can avoid the problem of "premature",help to improve the convergence speed of the model function,and have certain operability.Finally,the optimization model of drug cold chain logistics distribution path of a pharmaceutical company is solved,the logistics distribution path is determined,and the results of the optimization are analyzed.Through the research,we know that: the optimized cold chain logistics distribution of drugs in a pharmaceutical company has obvious improvement in distribution time,distribution mileage,total distribution cost,vehicle loading rate and other aspects,which improves the operation efficiency of the company,obtains good economic benefits,and has certain operability. |