The Treatment Method Of Tonifying The Liver And Kidney Deficiency Of The Liver And Kidney Of Rheumatoid Arthritis Clinical Study Of Secondary Osteoporosis

Objective: This study is to observe the effect of Tonifying the liver and kidney of liver and kidney deficiency type of rheumatoid arthritis with secondary osteoporosis and regulation.For the patients to improve the symptoms,reduce the rate of relapse and reduce the drug’s own adverse reactions and other aspects of treatment.Methods: A total of 80 patients with rheumatoid arthritis secondary osteoporosis in our hospital from January 2017 to December-2017 were selected.The patients were randomly divided into treatment group and control group with 40 cases in each group,and the allocation sequence was concealed.Control group: Leflunomide Tablets 20mg/ days,1 times a day,calcium carbonate D3 tablets 600mg/ days,1 times a day orally,Alfa alcalol 0.5 micron g/ days,1 times a day orally,when pain,plus Diclofenac Sodium Dual Release Enteric-coated Capsules 75mg/ times,1 times a day.The treatment group based on the blood of Rongjin Decoction: Rehmannia glutinosa 10 g,Cistanche 15 g,Gentiana 10 g,dodder 15 g,12g,10 g from Eucommia Achyranthes 15 g,papaya 10 g,angelica 8g,Gouji 15 g,wind 10 g,ginseng 10 g,angelica 15 g the prescription Decoction to 200 ml sooner or later two times take,daily 1 agent,24 weeks for 1 courses.Case evaluation was performed before treatment,joint tenderness,morning stiffness,joint pain index,joint swelling number of observation,average grip strength of both hands and 15 m walking time,calculate the 28 joint disease activity score(Disease activity scorein 28 joints,DAS28),calculate the pain scale in pain score,which is the universal application of international visual simulation score(visual analogue scale,VAS pain score,erythrocyte sedimentation rate(Erythrocyte)by sedimentaction rate,ESR),C reactive protein(C-reactive protein,CRP),rheumatoid factor(Rheumatoid factor,RF)and anti cyclic citrullinated peptide antibody(Anti-cyclic citrullinated,peptide,Anti-CCP),bone alkaline phosphatase(bone alkaline phosphatase,BALP(Serum Calcium),serum calcium,serum phosphorus(S-Ca),Serum Phosphorus,S-P),dual energy X-ray bone The density(bone mineral density,BMD)was measured(the BMD of the lumbar spine and the neck of the femur,respectively).The treatment began for 24 weeks and 1 courses of treatment.After 12 weeks of treatment,the observation cases were evaluated for 1 times.After the treatment of 1 courses,the above observation indexes were remeasured.Results:The Two groups before treatment were observed no significant differences(P > 0.05),comparable;the two groups after treatment of the symptoms,signs and laboratory examinations of most improved or returned to normal;the treatment group than the control group(P < 0.05);the two groups before and after treatment were compared.The difference was statistically significant(P < 0.05),compared to 22 among the two groups,the difference was statistically significant(P < 0.05);Conclusion: All two groups can improve the symptoms,signs and laboratory results of RA secondary OP patients,and the effect of combined therapy is better than that of the western medicine group.The adverse reaction of this combined therapy was less than that in the simple western medicine group.