The Role Of Thromboelastography In Guiding Blood Transfusion Of Infant Undergoing Open-Heart Surgery With Cardiopulmonary Bypass

Objective To investigate the role of thromboelastography and coagulation tests in guiding blood transfusion of infants undergoing open-heart surgery with cardiopulmonary bypass.Methods This study of 60 children within 12 months undergoing cardiac surgery with cardiopulmonary bypass(CPB)were divided into TEG guide blood transfusion group(Experimental group)and coagulation tests guide blood transfusion group(Control group).The volume of different components of transfused blood,the volume of postoperative bleeding,and complications after cardiac surgeries were compared in two groups.Results The blood transfusion volume in experimental group(50.3±31.4 ml)was significantly lower than that in control group(64.7±46.8 ml),and the FFP infusion volume(25.5±34.2 ml vs.63.6±50.8 ml,P<0.05)as well as the aryoprecipitate infusion volume(0.13±0.33 U vs.0.35±0.45 U,P<0.05)in experimental group were significantly lower than those in control group.The platelet infusion volume in experimental group(0.93±1.17 U)was significantly higher than that in control group(0.37±0.89 U).The volume of thoracic cavity drainage after surgeries in experimental group was significantly lower than that in control group(59.07±10.13 ml vs.72.57±15.29 ml,P<0.05).There were no postoperative complications in two groups.Conclusion TEG in guiding blood transfusion of infant undergoing open-heart surgery with cardiopulmonary bypass can reduce the volume of allogeneic blood products and the postoperative bleeding in infants after CPB.It may provide a strategy for guiding clinical blood transfusion.