The Applications Of DKI Techniques In Persistent Vegetable State

Objective: To investigate the microstructure changes in persistent vegetable state by using the new technology of Diffusion Kurtosis Imaging(DKI)Methods: conventional MRI and DKI were performed in 20 age-matched normal volunteers and 15 patients with VS which are collected.The MK、MD in thalamus,internal capsule,corpus callosum,the corpus callosum,the bilateral temporal cortex and the brain stem were quantified using DKI.Results:the mean kurtosis(MK)value of the thalamus,corpus callosum,the bilateral temporal cortex and the brain stem were significantly lower than those in the normal control group(P < 0.05).The mean kurtosis(MD)value of the thalamus,internal capsule,corpus callosum,the corpus callosum,the bilateral temporal cortex and the brain stem were significantly higher than those in the normal control group(P < 0.05).Conclusion: DKI can provide objective referential indexes for the trauma extent and range in VS.