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Clinical Analysis Of 200 Cases Of Abdominal Wall Endometriosis

Posted on:2019-03-31Degree:MasterType:Thesis
Country:ChinaCandidate:Y S WuFull Text:PDF
GTID:2394330548459138Subject:Clinical Medicine
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Background and Objective:Endometriosis(EM)refers to the growth of endometrial tissue(glands and interstitium)in the uterine cavity covering the intima and other parts of the body outside the muscle layer,is the most reproductive age women One of the common diseases.The clinical manifestations of the disease are diverse,and although histologically benign,it has malignant behaviors such as hyperplasia,invasion,metastasis,and recurrence.Ectopic endometrium can invade any part of the body,but the vast majority is located in the pelvic cavity,and the ovaries are the most commonly affected sites.Abdominal wall endometriosis(AWE)refers to the growth of endometrial tissue with abnormal growth on the abdominal wall,which is the most common extraluminal endometriosis.After most AWE secondary to caesarean section,the painful nodules that gradually increase around the abdominal wall incision are the most common manifestations of AWE.In recent years,with the high rate of cesarean section surgery in our country,the incidence of abdominal wall endometriosis has also increased year by year.The disease can cause many symptoms that make patients suffer and severely affect the ability of daily activities,such as pelvic pain,severe dysmenorrhea,painful intercourse and infertility.This study retrospectively analyzed the clinical data of 200 patients with abdominal wall endometriosis admitted to the Peking Union Medical College Hospital from 2006 to 2017.The effect of different postoperative treatments on the recurrence rate after 5 years was analyzed.The occurrence of the disease and the related factors of prognosis,hope to provide reference for reducing the occurrence and recurrence rate of abdominal endometriosis in the future.Methods:The clinical data of 200 patients with abdominal endometriosis who had been surgically removed and confirmed by postoperative pathology were retrospectively analyzed and followed up by telephone.The results were analyzed by SPSS 17.0 software.Results:1.Spearman correlation analysis showed that the latency of AWE was positively correlated with the age of onset(r=0.296,P<0.001).The difference was statistically significant;the latency was negatively correlated with the menstrual cycle and menstruation,but the difference was not statistically significant.2.Patients with age >30 years(112 cases)had significantly longer latency than those with age ?30 years(88 cases).The difference was statistically significant(z=-3.317,P=0.001).Patients with a menstrual cycle of ?28 days have a longer incubation period than those with a period of <28 days.Patients with a menstrual period of ?5 days have a longer incubation period than patients with a menstrual period of more than 5 days.However,there is no significant difference in the effect of the two factors on the latency(z=-0.987,P = 0.323;z =-0.356,P = 0.722).3.The treatment was surgical resection of the lesion,the margin of the lesion was 0.5 cm from the edge of the lesion,and 46 patients were treated with adjuvant therapy.4.200 patients were followed up successfully in 146 cases,and the cumulative 5-year recurrence rate was 5.72% Conclution:1.Most of AWE are secondary to cesarean section.2.The onset age of the abdominal wall endometriosis patients are the influencing factors of the incubation period.3.Lowering the cesarean section rate and protecting the incision can reduce the AWE rate.4.Ultrasound can underestimate the size of the lesion.5.The recurrence rate of AWE is low.The lesion diameter and previous history of AWE have influence on the recurrence of abdominal wall endometriosis.
Keywords/Search Tags:Abdominal wall endometriosis, Incubation period, Incidence, Recurrence
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