An Epidemiologic Study Of Function Dyspepsia And Irritable Bowel Syndrome In The Military In Southest China

BackgroundFunctional gastrointestinal disease(FGIDs)refers to a group of recurrent gastrointestinal symptoms,which can not be explained by structural or biochemical abnormalities of the functionality of digestive diseases.Functional dyspepsia(FD)and irritable bowel syndrome(IBS)are the most common entities among FGIDs.The prevalence of FGIDs varies from different regions and ethnicities.FD is the most common cause of dyspeptic symptoms.IBS is a gastrointestinal functional disorder characterized by abdominal pain or discomfort,and bowel habit change.Mental psychological factors are supposed to be associated with the pathogenesis of FD and IBS.There are few epidemiological studies on FGIDs in military in China.Due to the special lifestyle,high-intensity training and other characteristics,especially the stress of responding to emergencies,combat or other situations,the prevalence of FGIDs may be high in the military.This will directly affect the combat effectiveness of our army.This epidemiological study for the first-line soldiers in the southeast China,was carried out to investigate the prevalence and related risk factors of FD and IBS,to pave the way for further prevention,diagnosis and treatment of functional gastrointestinal disease in the military.ObjectiveTo explore the prevalence and risk factors of functional dyspepsia(FD)and irritable bowel syndrome(IBS),and to analyse depression and anxiety in the military in southeast China.MethodsThe questionnaire survey based on Rome ? Criteria were carried out among 3106 soldiers in southeast China using stratified cluster random sampling method.Scores of anxiety and depression were detected with Self-Rating anxiety scale(S AS)and Self-Rating depression scale(SDS).Statistical analysis was performed using SPSS 20.0,and P<0.05 was considered statistically significant.T test was used for detecting the difference of measurement data,chi-square test for enumeration data,and non-Parametric test for ranked data.Logistic regression was used for multivariate analysis.Odds ratio(OR)with 95%confidence interval(CI)was calculated.ResultsA total of 3,106 soldiers were surveyed and all questionnaires were collected,of which 2918 were valid with an effective rate 93.95%(2918/3106).The overall prevalence of FD was 6.1%,among which the prevalence of male soldiers was 6.0%,the prevalence of female soldiers was 6.5%,and the ratio of male and female prevalence was 1:1.08.Univariate analysis showed that FD was associated with age,weight,BMI group,marital status,educational level,rank level,smoking including passive smoking,tea,drinking,daily routine,dietary law,sleep quality,SAS scores and SDS score,digestive disease history,chronic medical conditions(P<0.05).Logistic regression analysis showed that age(OR=1.126,95%CI:1.083-1.170),chronic medical conditions(OR=1.686,95%CI:1.041-2.732),digestive diseases history(OR=1.771,95%CI:1.140-2.751),smoking including passive smoking(OR=5.002,95%CI:1.550-16.27),irregular diet(OR=2.084,95%CI:1.131-3.843)and poor sleep quality(OR=2.284,95%CI:1.339-3.895)were the most likely risk factors.The general prevalence of IBS was 7.3%according to the Rome ? Criteria,among which the prevalence of male soldiers was 6.9%,and female soldiers 13.7%.There was a female predominance with ratio of male to female as 1:1.98.Univariate analysis indicated that IBS was related to gender,age,weight,BMI group,marital status,educational level,rank level,drinking,daily routine,sleep quality,SAS and SDS score,long-term medication,digestive disease history,chronic medical conditions.Factors including gender(OR=2.577,95%CI:1.493-4.448),family history of chronic disease(OR=1.686,95%CI:1.020-1.975),digestive disease history(OR=1.969,95%CI:1.367-2.836),long-term medication(OR=3.370,95%CI:1.694-6.705),BMI group(BMI?28.0,OR=2.745,95%CI:1.271-5.931),scores of SAS(OR=1.026,95%CI:1.014-1.038),poor sleep quality(OR=2.543,95%CI:1.604-4.031)were significantly associated with the presence of IBS.The prevalence of depression was 51.4%(mild 13.6%,moderate 18.9%and severe 19.0%),while that of anxiety was 41.6%(mild 26.2%,moderate 10.2%and severe 5.0%).ConclusionThe prevalence of FD was 6.1%in the military in southeast China.Age,chronic medical conditions,digestive diseases history,passive smoking,irregular diet and poor sleep quality were the potentially risk factors for FD.The general prevalence of IBS was 7.3%.Gender,family history of chronic disease,digestive disease history,long-term medication,BMI group,scores of SAS,poor sleep quality were the risk factors for IBS.Particular attention should be paid to the high prevalence of anxiety and depression in the military in southeast China.