The Clinical Analysis Of Influencing Factors Of Patients' Prognosis With Intracranial Ruptured Aneurysms After Surgical Treatment

Objectives:Retrospective study and analysis of the clinical data and imaging data of the patients with intracranial ruptured aneurysms at the Second Affiliated Hospital of Kunming Medical University,to explore prognostic factors associated with aneurysm clipping in the treatment of intracranial ruptured aneurysms.Provide guidance for clinical practice to improve the prognosis.Methods:Collecting the clinical data and imaging data of 186 patients with ruptured intracranial aneurysms admitted in department of neurosurgery,Second Affiliated Hospital of Kunming Medical University from July 2013 to October 2017,and conform to the criteria for inclusion,alignment and exclusion.They were grouped according to age,sex,smoking,drinking history,hypertension history,CT Fisher classification,Hunt-Hess classification,timing of operation,number,location and size of aneurysm,width of tumor neck,interruption during operation,and intraoperative rupture.And compared foe each group,the Glasgow Outcome Scale(Glasgow Outcome Scale,GOS)score results.Chi-square test and Logistic regression analysis were used by SPSS 17.0 statistical analysis software to analysis the clinical data.Results:Aotal of 186 patients were included in the study,of which 136(73.1%)had good prognosis and 50(26.9%)had poor prognosis.Single factor analysis results show that:?The difference of prognosis of patients with different ages was not significant(P>0.05);?The difference of prognosis of patients with different sex was not significant(P>0.05);?There was no significant difference in the prognosis of patients with the history of smoking or drinking alcohol or not(P>0.05);?There were significant differences in prognosis in patients with or without hypertension(P<0.05);?The patients with different CT Fisher grades had significant difference in prognosis,and there was statistical meaning(P<0.05);?The difference of prognosis of patients with different Hunt-Hess classification was significant,and there was statistical meaning(P<0.05);?The difference of prognosis of patients with different operation time was not significant(P>0.05);?The difference of prognosis of the patients with different aneurysms was not significant(P>0.05);?The prognosis of aneurysm patients with ruptured aneurysms in different positions was significant(P<0.05);?The difference of prognosis of patients with different aneurysms was not significant(P>0.05);(?)The difference of prognosis of aneurysm patients with different neck width was significant(P<0.05);(?)The effect of interruption on the prognosis of the patients was not significant(P>0.05).;(?)The effect of re rupture on the prognosis was not significant(P>0.05);Conclusions:(1)Hypertension,Fisher classification,Hunt-Hess classification(? and?),location of aneurysm and width of aneurysm neck are independent risk factors for prognosis of ruptured intracranial aneurysms.(2)Age,sex,smoking and drinking history,timing of operation,number of aneurysms,size of aneurysms,interruption and interruption during operation were not significantly correlated with prognosis,but not independent prognostic factors for intracranial ruptured aneurysms.