| Objectives To investigate the characteristics of α-wave activation in different regions of patients with post-stroke depression.The difference of response to different emotional stimuli in patients with post-stroke depression was also analyzed.The relationship between the degree of emotional response and the degree of depression,the degree of neurological deficit and the ability of living self-care in patients with post-stroke depression.Methods 124 stroke patients in Department of Neurology,affiliated Hospital of North China University of Technology were selected as the case group.A total of 62 health examiners from the affiliated Hospital of North China University of Technology were selected as the control group.The self rating Depression Scale(SDS),the National Institutes of Health Stroke Scale(NIHSS)and the modified Barthel index rating scale(MBI)were used to measure stroke patients.According to the inclusion criteria and exclusion criteria,the patients were divided into PSD group and post-stroke nondepression group,each group was 62 participants.Divide each group into two groups,31 participants in each group.Positive and negative emotional stimuli were carried out in each group.An electroencephalogram(EEG)examination for participants with positive emotional stimuli at 7 minutes after emotional stimulation.Then do brain electricity and topography inspection.All the data were processed statistically by SPSS19.0 software.The difference of P< 0.05 was statistically significant.Results 1 The results of EEG topographic examination after positive emotional stimulation showed that there was no significant difference in the number of activation in the left and right hemispheres,frontal lobe,temporal lobe and occipital lobe between the control group and the PSD group.(P>0.05).2 The results of EEG topographic examination after negative emotional stimulation showed that there was no significant difference between the control group and the PSND group(P>0.05).The number of α-wave activation in the frontal lobe,temporal lobe and occipital lobe in PSD group was higher than that in control group(χ~2=10.867)and in PSND group(χ~2=9.857).In the left hemisphere,the number of brain α waves in the right hemisphere was higher than that of the control group(χ~2=16.660)and PSND group(χ~2=10.801).The difference was statistically significant(P<0.05).3 After negative emotional stimulation,the severity of depression in patients with post-stroke depression is related to the number of alpha-wave activation areas in the brain(r=0.67,P<0.05),The degree of mild depression(r=0.89,P<0.05)and moderate depression(r=0.80,P<0.05)were positively correlated with the number of alpha-wave activation areas in the brain,4 After negative emotional stimulation,the degree of neurological deficits is related to the number of brain alpha activations(r=0.66,P<0.05),The degree of mild neurological deficits(r=0.59,P<0.05)and the degree of moderate neurological deficits(r=0.68,P<0.05)are positively correlated with the number of brain alpha activations,The degree of severe neurological deficit is negatively correlated with the number of brain alpha activations(r=-0.98,P<0.05).5 After negative emotional stimulation,the self-care ability of patients with post-stroke depression was not significantly correlated with the number of activated brain alpha waves(r=-0.11,P>0.05).6 Mild degree of depression is positively correlated with activation of left frontal lobe(P<0.05).Other depression severity,degree of neurologic impairment,and degree of self-care ability in the experiment were not significantly related to the activation amount of left frontal lobe and right frontal lobe in this experiment(P>0.05).Conclusions 1 The response to negative external emotional stimuli in patients with poststroke depression is different from that in the non-depressed group,and brain-electricity topography can be used as a supplementary examination method.2 The degree of emotional response of patients with post-stroke depression is easily affected by their degree of depression and neurological impairment. |
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