Clinical Characteristics And Influencing Factors Of Pulmonary Thromboembolism Combined With Deep Venous Thrombosis Of Lower Extremities

Objective To investigate the clinical features and influencing factors of pulmonary thromboembolism(PTE)in patients with pulmonary thromboembolism(PTE)combined with deep venous thrombosis(DVT)and pulmonary thromboembolism(PTE)without deep vein thrombosis(DVT).What are the differences in clinical features and influencing factors between PTE patients with lower extremity DVT and PTE patients without DVT in lower extremities? Method 1 Subject 202 patients with PTE diagnosed at the North China University of Technology Affiliated Hospital between December 2015 and December 2017 were included.Among them,133 patients with DVT of lower extremity(case group)and 69 patients without DVT of lower extremity(control group)).2 Data Collection General information collected from patients: age,gender;clinical features: clinical symptoms,clinical signs,risk stratification,blood routine,blood gas analysis,coagulation series,blood biochemistry,lower limb blood vessel ultrasound,echocardiography,CTPA;Influencing factors: History of BMI,smoking history,history of cardiovascular and cerebrovascular diseases,history of respiratory diseases,history of hyperlipidemia,hyperuricemia,malignancy,type 2 diabetes,history of vascular disease,surgical history within three months,trauma within three months History,brake history,oral contraceptives,pregnancy,postpartum 2 months.SPSS20.0 software was used for statistical analysis of the data,with P<0.05 as the difference was statistically significant.Results 1 There was no significant difference in age and gender between the case group and the control group(P>0.05).2There was no significant difference in risk stratification between the case group and the control group(P>0.05).The dyspnea,cough,sputum,pleural inflammatory pain,hemoptysis,and premenorrhalgia in the case and control groups were not significant.There were no significant differences in fever,palpitations,syncope and other clinical symptoms(P>0.05).The edema in the lower extremities was significantly higher in the case group than in the control group(P<0.05),and the pleural inflammatory pain was lower in the case group than in the control group(P<0.05);There was no statistically significant difference in blood parameters such as blood routine,biochemical and coagulation parameters,and blood gas analysis between the control group and the control group(P>0.05).The D-dimer level in the case group was significantly higher than that in the control group(P<0.05).3 Influencing factors: case group and control group in cardiovascular and cerebrovascular diseases,respiratory diseases,hyperlipidemia,hyperuricemia,malignant tumors,immune diseases,varicose veins,surgical history within three months,pregnancy,and postpartum There was no significant difference in the left heart enlargement and pulmonary hypertension between February(P>0.05).The diabetes in the case group,brake history within three days,trauma history within three months,oral contraceptives,right heart enlargement were significantly higher in the case group(P>0.05).P <0.05),significantly lower than that of the control group(P <0.05).4.Logisgic regression analysis: The statistically significant indicators were included in the regression equation.The last three days of the braking history(P = 0.030,OR = 2.264,95% CI: 1.082-4.735),diabetes(P = 0.039,OR=8.758,95% CI: 1.114 to 68.880),lower extremity edema(P=0.000,OR=13.139,95% CI: 5.193 to 33.244),high D-dimer level(P=0.042,OR=1.938,95% CI: 1.025 to 5.433)and PTE were associated with lower extremity DVT,while pleural inflammatory pain(P=0.016 OR=0.447,95% CI: 0.232 to 0.861)was associated with PTE without DVT in the lower extremities.Conclusion 1.The clinical features of patients with PTE combined with DVT are more likely to manifest as lower extremity edema,pulmonary aortic thrombosis,D-dimer levels are significantly higher,and pleural inflammatory pain is not easy to appear;2.High levels of D-dimer,diabetes,3 Within a day of braking history,lower extremity edema suggests that PTE patients have a higher risk of DVT associated with lower extremities.3.Pleural inflammatory pain suggests that PTE patients have a lower risk of DVT associated with lower extremities.