Analysis Of Correlation Between Body Mass Index And The Pathogenesis Of Multiple Sclerosis

Objective:To analyze the body mass index(BMI)levels in patients with multiple sclerosis(MS)and clinical isolated syndrome(CIS),and to explore the role of BMI in the pathogenesis of MS and CIS,and to provide help for the pathogenesis and treatment of these patients.Methods:To collect 91 MS patients,4 CIS patients of the age,height,weight,at the same age and sex ratio in healthy population of similar age,eight,weight,from January 2013 to July 2017,in the neurology department of First Affiliated Hospital of Chongqing Medical University,and to score MS and CIS patients by the criterion of expanded disability status scale(EDSS).To use SPSS 21.0 to analysis its risk factors and the relationship between it with BMI,and P<0.05 is meaning.Results:1.The male to female ratio of MS is 1:1.71,the average age is 30.16±13.81 years old,the predilection age is 20-50 years old.2.BMI>24 kg/m2 is a risk factor in the MS population(OR= 1.51),male(OR=2.49),and female(OR=1.16).3.There was a positive correlation between EDSS score and BMI value in MS group(r = 0.42,P<0.05).Conclusion:1.MS usually occur in the female of 20 to 50 years old.2.BMI>24 kg/m2 can be the risk factor of MS.3.The degree of MS nerve function damage was positively correlated with BMI value.