The Clinical Application Of Coronary Artery Calcification Score With Multi-slice Spiral CT In The Diagnosis Of Coronary Artery Disease And Its Relevance With Left Ventricular Function

Objective:To investigate Coronary Artery Calcification Score's(CACS)correlation with Age,Gender and coronary artery stenosis and to find the relevance between CACS and left ventricular function.Methods:We reviewed the data of 78 patients who underwent both multi-slice spiral computed tomography coronary angiography(CTA)and echocardiography,then evaluated the correlation of CACS and coronary artery stenosis and left ventricular function.Results:The results showed that CACS had a positive relationship with age and the severity of coronary artery stenosis(r=0.389,0.361;P<0.01).For the subjects 50?70 years old,there was a statistical difference(r=0.3 89.0.361.P<0.05)between the calcification scores of the male and female.There was a negative correlation between Coonary artey calcium score and Left ventricular ejection fraction<50%(r=-0.93,P<0.05).Patients having a CACS of 100 or higher were showed to have positive correlation with regional wall motion abnormalities(RWMAs)(r=0.87,P<0.01).Conclusions:MS CT coronary calcification score can be applied to evaluate the severity of the coronary atherosclerosis and was correlated with the left ventricular RWMA,hence CACS could be used as a marker for the diagnosis of subclinical coronary artery disease in the clinical practice.