The Study On The Application Of The Bundle Hepatic Inflow Occlusion In The Resection Of Left Lateral Segment Liver Cancer In Adult Patients

Objective: To explore the Safety and feasibility of the bundle hepatic blood occlusion method in the resection of left lateral segment liver cancer in adult patients.Methods: Totally,83 patients performed confine operation of hepatic left lateral lobectomy due to liver cancer were selected from July 2015 to January 2018 in our hospital.They were randomly divided into three groups,group A with hepatic inflow occlusion(HIO,27 patients),group B with hemi-hepatic vascular occlusion(HVO,28 patients)and group C refers to bundle hepatic inflow occlusion(BIO,28 patients).The clinical outcomes included operation time,intraoperation occlusion duration,intraoperation hemorrhage,intraoperative transfusion rate,levels of serum alanine aminotransferase(ALT)and serum alanine aspartate aminotransferase(AST)in the 1st day,3rd day and 7th day after operation,rate of complications and total hospitalization duration.Results: There was no difference in the preoperative clinical characteristics,intraoperation occlusion duration,intraoperative transfusion rate and incidence of complications between the three groups.The volume of intraoperative hemorrhage in BIO group(median: 320ml)was significantly lower than that of HIO(median: 430ml)and HVO(median:450ml)group.No significant difference was observed in intraoperative hemorrhage between HIO and HVO group(P >0.05).The BIO group(143.6±26.4min)showed similar operation time to HIO group(137.4±33.2min),which exhibited reduced operation time than that of HVO group(165.3±29.7min).The level of ALT in BIO group showed no significant difference than that of HVO group,which was obviously lower than that of HIO group in the 1st day,3rd day and 7th day after operation.The similar outcome was observed in the level of AST in the first and third day after operation,while there was no difference in the 7th day.There was no difference in total hospitalization duration among the three groups.Conclusions: BIO is a safe,simple and effective operation method in liver resection.The clinical benefits are embodied in favorable blood occlusion effect,reduced hepatic injury.Therefore,it is suitable for left lateral segment liver resection in adult patients with liver carcinoma.