Clinical Study On The Treatment Of Children With Bronchiolitis Obliterans By The Method Of Relieving Asthma,Eliminating Phlegm And Supplementing The Lung

Background:Bronchiolitis obliterans is a chronic airflow limitation syndrome caused by the injury of bronchiolitis,and the main clinical manifestations are persistent or repeated cough,wheezing,and poor exercise tolerance.The incidence of this disease is increasing year by year in children,and most of them are bronchiolitis obliterans after infection.At present,there is no universal accepted criterion for its treatment,and its curative effect is not satisfactory.The disease seriously affects children’s health and quality of life,which is attracting extensive attention from pediatricians.Objectives:To explore the therapeutic effect of Tong closure,asthma,expectorant and lung supplementation in the treatment of children with bronchiolitis obliterans,and to provide objective and accurate data sources and theoretical basis for the treatment of the disease by combining traditional Chinese and Western medicine.Methods: In this study,the participants were divided into two groups: the treatment group and the control group.The treatment group 28 cases of children were collected during the period from December 2015 to June 2017 in the First Affiliated Hospital of Henan TCM university who were diagnosed with BO,treated with combination of traditional Chinese and Western medicine research methods:(TCM treatment tongbipingchuan decoction,and according to the combination of all the TCM syndrome with western medicine treatment;the recommended scheme in "Chinese Journal of Pediatrics" in the guidelines for the treatment of bronchiolitis obliterans in children).Control group: a total of 29 children diagnosed as BO in the same period in Henan children’s hospital were collected,according to the diagnosis and treatment standard of children with bronchiolitis obliterans in Chinese Journal of Pediatrics.Observe the clinical symptoms(symptoms and signs)and laboratory examination(pulmonary function and lung imaging)changes in the treatment group and the control group,fill in the case observation form,and establish the therapeutic effect score table,and make statistical analysis.Result:1.patients in the 1.treatment group were effective in 24 cases(85.71%)after June,4 cases(14.29%),21 cases in the control group after June(72.41%),8(27.58%),P<0.05,the treatment group was more effective than the control group,the difference was statistically significant.2.In the treatment group,18 cases(64.28%)were effective after March,10 cases were invalid(35.71%),24 cases were effective after June(85.71%),and 4 cases(14.29%)were invalid.P<0.05,there were significant differences in the analysis of results in different courses of treatment;in the control group,16 cases(55.17%)were effective after March,13 cases(44.82%)were invalid,21 cases(72.41%)were effective after June,and 8(27.58%)were invalid.P<0.05,the difference was statistically significant.3.The lung function VPTEF/VE and tPTEF/tE The difference between 6 months and before treatment was statistically significant(P<0.05).4.In the treatment group,the lung function VPTEF/VE and tPTEF/tE,the difference between 6 months and before treatment was statistically significant(P<0.05).5.there was a statistically significant difference in the imaging scores of the two groups after treatment(P<0.05).Conclusion: 1.the method of relieving asthma,eliminating phlegm and supplementing the lung was effective in the treatment of children with BO.2.long term treatment of children with BO treated with the method of relieving asthma,eliminating phlegm and supplementing the lung has a significant effect.