| Objective: To investigate the effect of chest pain center(CPC)protocol on the treatment and prognosis in patients with acute ST-segment elevation myocardial infarction(ASTEMI).Methods: 946 patients with ASTEMI were enrolled the study by cohort and divided into 6 groups,according to the non-CPC protocol period(group A),preparing period of CPC protocol(group B),pre-CPC protocol period(group C),initial stage of CPC protocol period(group D),post-CPC protocol period(group E)and late stage of CPC protocol period(group F).comparisons of revascularization,complication and prognosis in ASTEMI between 6 groups were analyzed.Results: 1.Compared with patients treated before chest pain center construction,those treated after chest pain center construction had shorter D-to-B times(groups A:117±53,groups B:141±88,groups C:127±90,groups D:73±23,groups E:74 ±38 and groups F:62±17)(P < 0.05).2.Compared with patients treated before chest pain center construction,those treated after chest pain center construction had lower ratio of in-hospital complications,such as atrial fibrillation(groups A: 15.4%,groups B: 9.8%,groups C: 3.3%,groups D: 6.2%,groups E: 7.2% and groups F:9.6%)(P < 0.05).3.With the establishment of CPC,the PPCI rate(groups A: 50.6%,groups B: 56.1%,groups C: 62.7%,groups D: 74.1% and groups E: 69.3% and groups F: 76.0%)were significantly increased in patients who suffered from ASTEMI(p<0.05).4.Compared with patients treated before chest pain center construction,those treated after chest pain center construction had lower ratio of in-hospital mortality(groups A: 8.6%,groups B: 8.1%,groups C: 8.0%,groups D: 1.9%,groups E: 7.2% and groups F:2.7%)(P < 0.05).Conclusion: The establishment of chest pain center could optimize the diagnosis and treatment of ASTEMI patients obviously,which can effectively shorten the emergency stay and D-to-B time.As reduction in-hospital complications and mortality by PPCI as soon as possible,then the prognosis of ASTEMI in hospitalization was improved. |
