Analysis Of Diagnosis And Treatment Of VTE In 99 Cases Of Patients With Advanced Malignant Tumor

Objective: To understand the treatment and prevention of patients with advanced malignant tumor combined with VTE,strengthen the cognition of tumor correlation VTE and improve the quality of life of patients and improve their prognosis.Method: From January 2012 to October 2016,the general situation of the tumor patients(hereinafter referred to as the VTE group)and the diagnosis,treatment and prevention of VTE were diagnosed as VTE in the fourth affiliated hospital of China Medical University.The non-VTE tumor patients who were admitted to the hospital at the same time were the control group(hereinafter referred to as the control group).Logistic regression analysis was performed on the data of the two groups of patients in order to look for possible VTE risk factors.Results: We chose 99 patients for the VET group and the control group respectively,the age of these patients were between 25-86.There are 64(64.4%)patients whose age was over 60,and 57(57.6%)patients whose ZPS scores were over 2.In the TNM stage of advanced malignant tumor,there were 34 cases(34.3%)in stage III and 65 cases(65.7%)in stage IV.There were 84 cases(84.8%)with color ultrasonography and 15patients(15.2%)with CT diagnosis.There were 71 cases(71.7%)in the lower extremity deep vein,13 cases(13.1%)in the upper limb deep vein,7 cases(7.1%)in the pulmonary artery,and 8 cases(8.1%)in the other parts.The clinical manifestations of deep venous thrombosis in lower extremities were mainly swelling,pain and skin temperature rise and the result were 35 cases(49.3%),13 cases(18.3%)and 4 cases(5.6%)respectively.Among the patients treated with VTE,49 patients(92.5%)were treated with low molecular heparin anticoagulation,and 17 patients were treated with urokinase thrombolysis;in the follow-up treatment after discharge,10 patients were treated with warfarin,but the time to be treated after discharge was not recorded;the majority of VTE group patients did not use preventive anticoagulation after diagnosis of tumor.In multivariate Logistic regression analysis,there was a statistically significant difference in the decline of hemoglobin,the extension of thrombin time,and the application of central venous catheter.The optimal truncation point was 0.395mg/m L for the ROC curve analysis of plasma D dimer.Conclusion: Malignant tumors combined with VTE occur in patients over 60 years of age,stage IV and poor activity;the location of VTE was mainly lower limb deep vein,and the diagnosis was mainly based on clinical manifestations,color Doppler ultrasonography and other related examinations.The treatment of tumor combined with VTE was mainly treated with low molecular weight heparin in the hospital,and the anticoagulation was taken by warfarin after discharge,but the follow-up treatment was insufficient and the treatment time was not clear.For patients with advanced tumor,VTE lacks active preventive measures and awareness.