The Research Of Relative Effective Factors Of Cervical Lymph Node Metastasis In Papillary Thyroid Carcinoma

Objectives: To assess the relative effective factors of papillary thyroid carcinoma(PTC)related to the metastasis of cervical lymph node.Methods: The clinical data of 82 patients with PTC was collected and retrospectively analyzed,who were treated in the Department of Pancreatic and Thyroid Surgery of Sheng Jing Hospital of China Medical University from January 2014 to March 2017.All patients underwent therapeutic cervical lymph node dissection.The relationship between the neck lymph node metastasis of different area and related metrics(such as patient's gender,age,tumor max diameter,multi-center,bilateral involvement)were analyzed after establishing the database.Univariate analysis were performed using ?2 test or Fisher's exact test,multivariate analyses were performed with the binary logistic regression model.It would be considered significant if P value is less than 0.05.Results: When PTC had local lymph node metastasis,most of metastasis transferred to central lymph node,second to lateral lymph node metastasis.According to lateral lymph node metastasis,level ? have highest metastatic rate,and then is the level IV.Univariate analysis showed that age<45years old,tumor max diameter>10mm,multi-center,bilateral involvement were remarkably related to central lymph node metastasis in papillary thyroid carcinoma(P<0.05).And multi-center were remarkably related to lateral lymph node metastasis(P<0.05).Multivariate analysis of binary logistic regression analysis demonstrated that age<45years old,tumor max diameter>10mm,multi-center were independent risk factors affecting central lymph node metastasis.Conclusions: The factors of patient with age<45 years old,tumor max diameter>10mm and multi-center were independent risk factors for central lymph node metastasis in PTC.The multi-center might increase the risk of lateral lymph node metastasis.