| Objective: To observe the clinical efficacy and safety of self-made Jianpi Zhixie Decoction in the treatment of diarrhea due to spleen deficiency in children,and to make a safe,objective and effective evaluation,so as to provide new methods and ideas for clinical treatment of the disease.Methods: 60 cases of children with spleen deficiency and diarrhea were collected from the pediatric clinic of the First Clinical Hospital of Jilin Academy of Traditional Chinese Medicine.They were randomly divided into treatment group and control group,30 cases in each group.The treatment group was given Jianpi Zhixie Decoction orally,while the control group was given Xingpi Yanger Granule orally,two weeks as a course of treatment,two consecutive courses of treatment were taken for comparison,followed up for one month.Results: There were 30 cases in the treatment group,including 1 case cured,19 cases markedly effective,9 cases effective and 1 case ineffective.The total effective rate in the treatment group was 93.33%.Of the 30 cases in the control group,there were 0 cases cured,0 cases markedly effective,26 cases effective and 4 cases ineffective.The total effective rate of the control group was 86.67%.After rank sum test P < 0.05(P 0.00),the curative effect of the treatment group was significantly better than that of the control group,with significant difference.It shows that Jianpi Zhixie Decoction has remarkable curative effect in treating diarrhea of spleen deficiency type in children.Conclusion: The self-made Jianpi Zhixie Decoction has remarkable clinical effect in treating diarrhea of spleen deficiency type in children.It is superior to Xingpi Yanger Granule in improving the efficacy of diarrhea of stool,loss of appetite,spirit and thirst in children.It is safe and has no toxic and side effects. |