The Clinical Research Of BaishiWenpi Decoction For Diarrheal Irritable Bowel Syndrome

ObjectiveTo explore the clinical efficacy of Baishiwenpi decoction in the treatment of diarrhea irritable bowel syndrome(IBS-D),in order to broaden the treatment ideas of this disease and explore new treatment options.MethodsSelect clinically met inclusion and exclusion criteria of 60 cases of patients with IBS-D,divided into the treatment group(30 cases)and control group(30 cases)in treatment group to baishiwenpi decoction,the control group give oral compound glutamine enteric capsule treatment,a course of 4 weeks,observe and record two groups of patients before and after defecate frequency,character,symptoms such as abdominal pain and bloating,sense of urgency to defecate,record the clinical symptoms of each single integral,clinical symptoms,TCM syndrome integral,total integral irritable bowel syndrome(quality of life scale score,anxiety self-assessment scale score,depression self rating scale score and withdrawal relapse after 4 weeks.Results1.Patients in the treatment group showed the most significant improvement in 7 symptoms:frequency of stool,stool traits,attack or aggravation after cold,sense of urgency to defecate,mental fatigue,lethargy,hand and foot hypothermia(P<0.01),and significant improvement in three symptoms:abdominal pain or abdominal discomfort,distension and fullness discomfort,and attack and impermanence(P<0.05).In the control group,the improvement of nerveless symptoms was the most obvious(P<0.01).The seven symptoms of stool frequency,stool traits,abdominal pain or discomfort-attack or aggravation after cold,mental fatigue and indolence hand and foot hypothermia were significantly improved(P<0.05),while there was no significant improvement in the two aspects of distension discomfort and attack impermanence(P>0.05).2.Patients in the treatment group showed better improvement in 8 symptoms,including stool traits,sen se of urgency to defecate,attack or aggravation after cold,fatigue,tepid hands and feet,numbness,swelling and discomfort in two parts,and impermanence,than those in the control group(P<0.05);After treatment,the frequency of defecation,abdominal pain or abdominal discomfort of the two groups of patients showed good improvement,and the difference was not statistically signi:ficant(P>0.05).3.There was no statistically significant difference in the total clinical symptom score between the two groups before treatment(P>0.05).After treatment,the total clinical symptom score of the two groups was significantly improved(P<0.05).but the improvement of the total clinical symptom score of the treatment group was significantly better than that of the control group(P<0.05).4.There was no statistically significant difference in the total score of quality of life before treatment between the two groups(P>0.05).After treatment,the quality of life was improved in both groups(P<0.05),but the improvement of quality of life in the treatment group was significantly better than that in the control group(P<0.05).5.The total effective rate of the treatment group was 86.67%,and that of the control group was 53.33%.The therapeutic effect of the treatment group was significantly higher than that of the control group(P<0.01).6..1There was no significant difference in the scores of anxiety and depression between the two groups before treatment(P>0.05).After treatment,anxiety and depression were improved in both groups(P<0.05),but the improvement of anxiety and depression in the treatment group was significantly better than that in the control group(P<0.05).7.26 patients in the treatment group were followed up four weeks after drug withdrawal,and 6 patients had recurrence,with a recurrence rate of 23.08%.Follow-up control group of 16 people,recurrence of 7 people,recurrence rate of 43.75%.The recurrence rate of the treatment group was significantly lower than that of the control group.Conclusion:Baishiwenpi decoction is effective in the treatment of diarrhea-type irritable bowel syndrome.It is effective in improving the clinical symptoms of discomfort,improving the quality of life,improving bad mood and reducing the recurrence rate,which is worthy of further study and promotion.ConclusionBaishiwenpi decoction is effective in the treatment of diarrhea-type irritable bowel sxyndrome.It is effective in improving the clinical symptoms of-discomfort.improving the quality of life,improving bad mood and reducing the recurrence rate,which is worthy of further study and promcotion.