Clinical Study On Acupuncture Combined With Moxibustion For Treating Abdominal Simple Obesity Of Insufficiency Of Spleen Deficiency And Dampness Type Complicated With Insulin Resistance

Objective:To explor the influence of the treatmeamt of acupuncture combined moxibustion on obesity,waist circumference,waist-to-hip ratio(WHR),waist-to-height ratio(WHtR),fasting plasma glucose(FPG),fasting insulin(FINS),the level of lipids and insulin resistance(IR)in patients with spleen deficiency and dampness type in abdominal simple obesity complicated with IR.Furthermore more,to investigate this treatment can improve the symptoms and signs of spleen deficiency and dampness type abdominal obesity patients effectively,and improve those patients' insulin sensitivity and reduce IR effectively.In Addiction,to compare the difference in efficacy of the treatmeamt combined acupuncture and moxibustion and conventional diet exercise therapy.Methods:60 cases eligible subjects were divided into a treatment gou pand a control group randomly,with 30 cases in each groups.Control group:only diet and exercise intervention treament were developed forthe subjects,the course of treatment was 80 days.Treatment goup: the treatment of acupuncture and moxibustion was added based on the control method of the control group.Acupoint selection:Zhongwan(CV12),Qihai(CV 6),and bilateral Tianshu(ST 25),Shuidao(ST 28),Zusanli(ST 36),Fenglong(ST 40),Yinlinquan(SP 9),Daheng(SP 15),Zhigou(TE 6),Daimai(GB 26);acupoint selection for mild moxibustion:bilateral Zusanli(ST 36),Fenglong(ST 40).In the treatment group,a needle for 30 minutes was given each treatment,once every other day,10 times for at reatment course,and 4 courses of the treatment in total for each subjects.Body weight,waist circumference,body mass index(BMI),waist-to-hip ratio(WHR),waist-to-height ratio(WHtR),body fat rate(F%),triglyceride(TG),total holesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholestero(HDL-C),fasting plasmaglucose(FPG),fasting insulin(FINS),insulin resistance index(HOMA-IR),insulin action index(IAI)were the observation indexs before treatment,one day after 4 courses of the treatment and a month after the treatment.Evaluate the spleen deficiency and dampness syndrome's syndrome score simultaneously.statistical analysis was performed on the data using SPSS 17.0 statistical software.Results:(1)After treanment,traditional Chinese Medicine syndrome score(TCM syndrome score),body weight,BMI,waist circumference,WHtR,F%,FPG,FINS,HOMA-IR,IAI(statistical analysis in the form of lnIAI in the paper,the same below),TG,TC,LDL-C,HDL-C of the treatment group and the control group were both inproved,compared with those before treatment(P<0.01 or P<0.05).(2)A month after the end of the treatment,the TCM symptom scores,body weight,BMI,waist circumference,WHtR,F%,FPG,FINS,HOMA-IR,IAI,TG,TC,LDL-C,HDL-C of the treatment group were still improved,compered with those before treatment(P<0.01 or P<0.05).While in the control group,the TCM symptom scores,body weight,BMI,FPG,FINS,HOMA-IR,IAI,TG,TC were improved(P<0.01 or P<0.05),and there was no statistical significance difference between waist circumference,WHtR,F%,LDL-C and HDL-C,compared with those before treatment(P>0.05).(3)There was no significant difference in WHR of the control group at times that before treatment,after treatment and a month after the end of the treatment(P>0.05),while the treatment group could improve WHR after treatment(P<0.05),and shows no significant difference between before treatment and a month after treatment(P>0.05).(4)After treatment and a month after treatment,there was no significant difference in WHR,FPG between the treatment group and control group(P>0.05),and the treatment group had better improvement in the remaining obesity signs,IR and lipid-related biochemical indicators,and TCM syndrome scores for spleen deficiency and dampness,compered with the control group(P<0.01 or P<0.05).Conclusions:The treatmeamt of acupuncture combined moxibustion can improve the symptoms and signs of spleen deficiency and dampness type abdominal obesity significantly,the curative effect is better than simple diet exercise.In particular,it has advantages in reducing body weight,waist circumference,WHtR,regulating FPG,FINS and the level of lipids effectively,increasing insulin sensitivity,and lowering insulin resistance.And these effects may have a certain sustained effect.