The Complications Of 192 Infants Of Gestational Diabetic Mellitus Mothers

Objective: To understand the complications of infants of Gestational Diabetic Mellitus mothers and explore the effect of prenatal HbAlc levels on the complications of neonates.To provide reference for clinical management of infants of GDM mothers.Methods:A total of 192 neonates of GDM mothers who were diagnosed as neonates with GDM were enrolled from January 2015 to December 2017.According to prenatal HbA1 c levels,GDM group were divided into HbA1c<6%(group A1)HbA1c≥6.0%(group A2).Retrospective analysis was used to observe the occurrence of complications in neonates and the relationship between HbA1 c level and neonatal complications.According to the relationship between gestational age and body weight,GDM group was divided into large for gestational age group(group B1)and not large for gestational age group(group B2).The difference in neonatal complications between the two groups was compared.Results:(1)The incidence of GDM in our hospital in 2015,2016,and 2017 was 16.19%,17.59%,and 19.46%,respectively,and the difference was statistically significant(P<0.05).(2)Among the 42 preterm infants,there were33 late preterm infants(78.57%);Among the 14 infants of malformation,there were 7 cardiovascular malformation(50%);And among the 17 infants of asphyxia,16 were mild asphyxia(94.12%).(3)In the GDM group,27 infants with hypoglycemia and 24 cases(88.89%)occurred within 2 hours of birth,and blood glucose levels increased after retreatment.(4)The incidence of neonatal hypoglycemia and large for gestational age in group A2(21.13% and 23.35%,respectively)was significantly higher than that in group A1(9.92% and 12.4%,respectively),the difference was statistically significant(P<0.05).There was no significant difference(P>0.05)in neonatal hyperbilirubinemia,preterm infants,asphyxia,birth trauma,malformation,RDS,and polycythemia among the two groups.(5)The incidence of neonatal hypoglycemia(27.27%)in group B1 was significantly higher than that in group B2(11.32%),and the incidence of preterm infants in group B2(25.16%)was significantly higher than that in group B1(6.06%),the difference was statistically significant(P<0.05).There was no significant difference(P>0.05)in neonatal hyperbilirubinemia,asphyxia,birth trauma,malformation,RDS,and polycythemia among the two groups.Conclusion:(1)The incidence of GDM in our hospital has been on the rise in the past three years.(2)Neonatal hypoglycemia in GDM group occurs mainly within 2 hours after birth and with a good prognosis,and Hypoglycemia is more likely to occur in large for gestational age.(3)The level of prenatal HbA1 c in GDM mothers is related to the incidence of neonatal hypoglycemia and large for gestational age.HbA1 c ≥ 6% is more likely to occur hypoglycemia and greater than gestational age.