Prevalence And Control Measures Of Helicobacter Pylori Infection In Population In Southwestern Shandong

Objective: To understand the prevalence of Helicobacter pylori(Hp)infection in the southwestern Shandong population and to explore the related prevention and treatment measures.Methods: A total of 13931 inspectors who underwent C14-urea breath test in our physical examination center from November 2017 to October 2018 were selected as subjects.The C14-urea breath test was used to detect the HP infection rate and the infection status of HP in different ages and genders in southwestern Shandong.The retrospective analysis also compared different academic qualifications,economic status,work nature,living conditions,regular physical examination and life behavior.(Smoking,drinking,staying up late,frequent meals,irregular diet)and the family history of HP infection rate;and analysis of the control of life behavior(smoking,drinking,staying up late,frequent dinner,irregular diet)for HP infected people Standard quadruple sterilization effect;to explore the risk factors of HP infection and its effective prevention and treatment measures.Results: The total HP infection rate in the southwestern Shandong population was 60.65%(8449/13931).The male HP infection rate was62.00%(4843/7812),which was significantly higher than that of female58.95%(3607/6119).The HP infection rates of <30 years old,30-45 years old,46-60 years old,and >60 years old age groups were 56.96%,62.27%,60.48%,and 59.69%,respectively,and the difference was statistically significant(P<0.05).Among the 30-45 age group and the >60age group,the male HP infection rate was 65.02% and 63.13%,respectively,which was higher than the infection rate of 58.58% and55.81% in the same age group.The difference was statistically significant(both P < 0.05).Different academic qualifications,economic status,work nature,living conditions,regular physical examination,life behavior and family history had an effect on the HP infection rate of the population,and the differences were statistically significant(P<0.05).The higher the education,the better the economic conditions,the mental labor,the solitary,the routine health checkup,the non-smoking and drinking,the infrequent dinner,the absence of gastric cancer,peptic ulcer,a history of atrophic gastritis,the HP infection rate is low.After the HP infection was corrected,the HP bactericidal rate was significantly increased,and the difference was statistically significant(P<0.05).Conclusions: The HP infection rate in the southwestern Shandong population is higher than the national average,and the male HP infection rate is higher than that of females.With the increase of age,the HP infection rate showed a gradual increase and then gradually decreased.The HP infection rate was the lowest in the <30 years old age group,and the HP-infected rate was the highest in the 30-45 years old age group,Men which in the 30-45 years old age group are the people with thehighest HP infection rates.Education,economic status,nature of work,living conditions,regular physical examination,life behavior and family history have an impact on the HP infection rate of the population.The higher the education,the better the economic conditions,the mental work,living alone,routine health check,no smoking,no drinking alcohol,infrequent meals,no history of gastric cancer,peptic ulcer,and atrophic gastritis have a low HP infection rate.Controlling alcohol,smoking,staying up late,and regular meals,and then correct HP treatment,can effectively improve HP eradication rate.