Clinical Characteristic Of Type H Hypertension And Analysis Of AngⅡand Ang(1-7) Leavl

Objectives To explore the clinical features of patients with H-type hypertension,and to analyze the levels of ang II and ang(1-7)in patients with H-type hypertension.Methods Hypertensive patients admitted to the Department of Cardiology of the Affiliated Hospital of North China University of Technology from September 2017 to November 2018 were enrolled.A total of 240 patients who met the inclusion criteria were enrolled in the study.According to the level of homocysteine(Hcy),the patients were divided into H-type hypertension group,a total of 154 cases;in the non-H type hypertension group,a total of 86 cases.Collect general data of patients;blood routine indicators;blood lipid indicators;renal function indicators;related indicators of cardiac ultrasound;dynamic blood pressure indicators;clinical related examinations;and collect patient plasma,ELISA method to measure plasma ang II and ang(1-7)levels.Statistical analysis was performed using SPSS statistical software.The clinical data of the two groups of patients were compared and the levels of ang II and ang(1-7)were analyzed.Results 1 H-type hypertensive patients had a statistically significant difference(P<0.05)compared with men [83(53.9%)vs.32(37.2%)].2 There was a statistically significant difference between low-density lipoprotein(2.94±0.90 vs.2.53±0.69)and apolipoprotein B(0.94±0.28 vs.0.81±0.24)in male H-type hypertensive patients compared with non-H-type hypertensive patients.(P<0.05);There was no significant difference in ang II and ang(1-7)levels,ambulatory blood pressure index,cardiac ultrasound index,renal function index,blood routine index and clinical correlation examination(P>0.05).3 Female H-type hypertensive patients with apolipoprotein A-1(1.35±0.23 vs.1.56±0.44),creatinine(62.00±12.91 vs.56.58±7.74),cervical vascular ultrasonography abnormalities [59(83.1%)vs.35(64.8%)] the difference was statistically significant(P<0.05);there was no significant difference between ang II and ang(1-7)levels,ambulatory blood pressure index,cardiac ultrasound index,and blood routine index(P>0.05).4 Regression regression analysis showed that apolipoprotein B levels OR=1.050(1.008-1.094)was associated with male H-type hypertension(P<0.05).Carotid atherosclerosis OR=1.051(1.010-1.095)and apolipoprotein A-1 OR=0.395(0.166-0.941)was associated with female H-type hypertension(P<0.05).Conclusions 1 Compared with non-H type hypertension,the level of apolipoprotein B in male patients with H-type hypertension increased;the proportion of female carotid atherosclerosis increased.2 There was no significant difference in plasma ang II and ang(1-7)levels between H-type hypertensive patients and non-H-type hypertensive patients.Figure 0;Table 19;Reference 76...