Correlation Between Functional Dyspepsia And Electrogasrography

Objective:To analyze the difference of gastric myoelectrical activities between different subtypes of functional dyspepsia(FD).Methods:From September 2016 to June 2017,59 patients with functional dyspepsia included in outpatient and hospitalization Department of Liaocheng People's hospital were divided into two subtypes,namely postprandial distress syndrome(PDS)and epigastric pain syndrome(EPS),according to the Rome III diagnostic criteria.41 cases were included in PDS Group,18 cases were included in EPS group.The control group was 22 cases of healthy people from the physical examination Center.The dominant frequency,dominant power,dominant frequency average,dominant power mean,coefficient of variation,percentage of normal slow wave,main power percentage and power ratio of the three groups were evaluated by electrogastrography.Results:1.Symptomatic assessment:The two types both had abdominal pain and abdominal burning sensation,and group EPS patients were more serious than PDS(P<0.05).Abdominal distention and early satiety were more obvious in the PDS group,and those in group EPS patients were negligible(P<0.05).There was no difference in other symptoms between the two groups(P>0.05).2.Comparison of gastric electrical parameters:In group PDS,the main frequency coefficient of variation in postprandial was higher than that in pre meal(P=0.002);The coefficient of variation of dominant power before meal was higher than that in postprandial(P=0.044);The percentage of normal slow wave rhythm in postprandial was higher than that in pre meal(P=0.002);The incidence of gastric tachycardia in postprandial was higher than that in pre meal(P=0.000);There was no significant difference between the main power wether in pre or after the meal(P=0.071).In group EPS,the main power of post meal was higher than that in pre meal(P=0.043).In the control group,the postprandial power was significantly higher than that in pre meal(P=0.00).The comparison of frequency distribution showed that the frequency was mainly distributed in 2.4cpm-3.7cpm whether before or after a meal(P= 0.000,0.000,0.000,respectively)(P= 0.000,0.000,0.000,respectively);the comparison of power distribution showed that the power value in the 1.0-2.4cpm range accounted for the highest percentage of the total power whether before or after a meal(P=0.000,0.000,0.000,respectively)(P=0.020,0.010,0.020,respectively).The comparison of the main frequency between the three groups showed that the main frequency of the PDS group was lower than that of the EPS group and the control group,but the difference was not statistically significant(P=0.670).There was no significant difference in PR values between the three groups(P=0.289),but the PR values were higher in the control group than that in the EPS group,and of the group EPS was higher than that in the PDS group.Proportions of PR?1.0 among the PDS?EPS and control groups were significantly different(P=0.012),there was significant difference between the PDS and control group(P=0.06),and no significant difference between the EPS and control group(P=0.31).Conclusions:1.There was a certain overlap between the two subtypes of functional dyspepsia.Postprandial distress syndrome(PDS)patients were characterized by early satiety and postprandial fullness,which was associated with eating.Epigastric pain syndrome(EPS)patients were mainly abdominal pain and upper abdominal burning feeling,which were usually not related to eating.2.Compared with the control group,the patients in group PDS had abnormal gastric electrical activities,suggesting that the abnormal gastric electrical activities were one of the pathogenesis of postprandial distress syndrome.Changes of gastric electrical activities in the EPS group were similar to those in the control group,which were different from those in the PDS group.3.The electrogastric parameters between the two subtypes vary greatly,which has a certain guiding effect on clinical classification.It also suggests that the pathogenesis of the two subtypes is different,and further research is needed.4.By comparing the parameter changes of same individual between postprandial and preprandial,the parameter changes of different individuals,the effects of different physical state,individual differences were more systematic,rigorous understood.5.Analysis of the frequency distribution and power distribution,whether in healthy subjects or patients with functional dyspepsia,the frequency is mainly distributed within the normal range.Although the incidence of gastric electrical rhythm disorders in PDS patients was higher than that of normal subjects,the overall gastric myoelectric activity disorder was not so severe that the percentage of gastric tachygastria or bradycardia was significantly higher than that of normal slow waves.This result can also explain that the symptoms of FD patients are mild to moderate,rather than extremely severe gastrointestinal symptoms.The power is mainly distributed in the slow-moving zone,suggesting that strong and slow gastric contractions can ensure normal gastric function(creep,digestion,absorption).