| Objective:Observe the clinical efficacy of Jianpi Qingre Lishi Decoction in the treatment of spleen deficiency and dampness-heat type 2 diabetes mellitus with abdominal obesityMethods:Eighty cases of elderly patients with type 2 diabetes mellitus with abdominal obesity,spleen deficiency and damp-heat type were randomly divided into the control group and treatment group on average.The control group was given basic treatment(diet control,exercise therapy)+metformin hydrochloride enteric coated tablet intervention;the treatment group was given Jianpi Qingre Lishi Decoction intervention on the basis of the above program,4 weeks as a course,after 3 courses.Observe the two groups of blood glucose(fasting blood glucose,2 hours postprandial blood glucose),glycated hemoglobin,blood lipids,weight,waist circumference,body mass index,insulin resistance index,visceral fat area index,TCM syndromes and other data,Changes before and after treatment,and summarize data for statistical analysis.Results:1.During the treatment period,6 patients lost their contact because of no follow-up visits.Three patients in the treatment group fell off and 37 patients were eventually included in the study;The control group was lost in 3 cases and finally 37 patients were included in the study2.In the treatment group,FPG,2hPBG,HbAlc,TC,TG,HOMA-IR,BMI,TCM syndrome total score,TCM single syndrome score(except for abdominal distention)were significantly improved,which showed a large difference in data compared with the control group(P<0.01).In improving body weight,waist circumference,visceral fat area,there was a statistical difference(P<0.05).But they all were effective in HDL-C,LDL-C and WAN abdominal distention(TCM symptoms),the difference was not statistically significant(P>0.05)3.The effect was more obvious in the treatment group,with a total rate of 86.49%.While the total effective rate of the other group was 62.16%.And the difference was statistically significant(P<0.01).In terms of weight and overall waist effect,the effect was more obvious in the treatment group,with a total rate of 89.19%.While the total effective rate of the another group was only 64.87%.The difference was statistically significant(P<0.05)4.During the observation of this study,no adverse reactions occurred in both groups of patientsConclusion:Jianpi Qingre Lishi Decoction can significantly improve the relevant Chinese medicine symptoms of elderly patients with type 2 diabetes and abdominal obesity,and can reduce blood glucose,blood lipid,insulin resistance index,weight,waist circumference,body mass index,visceral fat area index,And it is safe and effective,without obvious adverse reactions,it is worthy of clinical promotion and application... |
