Clinical Study On The Treatment Of Spleen Deficiency And Damp-fever Type Ulcerative Colitis With Torrey’s Purulent And Spleen Dehumidification Method

Objective: Observe the clinical efficacy and safety of using Tori’s purulent method,spleen strengthening and dehumidifying method to treat ulcerative colitis with spleen deficiency and damp heat.Methods: According to the random number table method,66 patients with ulcerative colitis who met the inclusion criteria were divided into two groups,a treatment group and a control group of 33 each.There were 3 cases in the treatment group,2 cases in the control group,61 effective cases,30 cases in the treatment group and 31 cases in the control group.The treatment group took oral Chinese medicine Tongpu Sanhe Lianli Decoction;the control group took oral mesalazine enteric-coated tablets(trade name: Huidi,Jiamusi Luling Pharmaceutical Co.,Ltd.,specification: 0.25 g,National Pharmaceutical Standard H19980148).Enteroscopy,inflammatory bowel disease quality of life(IBDQ)table scores and inflammatory indicators were measured before treatment and after 8 weeks of treatment.Before treatment,after 4 weeks of treatment,and after 8 weeks of treatment,fill in the main symptoms and minor points Symptom score and Mayo score form,followed up for 3 months,record whether there are adverse reactions and recurrence,and statistical analysis,and draw conclusions.Results:(1)According to the TCM symptom curative effect score,the total effective rate of the treatment group is 90.00%,and the total effective rate of the control group is 83.87%.According to the Mayo score,the total effective rate of the treatment group is 93.40%,and the total effective rate of the control group is 87.10%.Compared with the effective rate,the difference was statistically significant(P<0.05);(2)After 8 weeks of treatment,TCM symptom scores were compared(abdominal pain,frequent bowel movements,rapid anxiety,weight loss,anorexia,dry mouth and bad breath,bitter and bad breath),Mayo score comparison(Number of bowel movements,doctor’s overall evaluation),inflammatory bowel disease quality of life(IBDQ)score comparison(systemic symptoms,social ability,emotional ability)were statistically different(P<0.05),the treatment group was better than the control group;(3)treatment After 8 weeks,there was no statistically significant difference in the comparison of Chinese medicine symptom scores(submucosal pus and blood),Mayo score comparisons(colonoscope,blood in the stool),and inflammatory bowel disease quality of life(IBDQ)table scores(intestinal symptoms)(P> 0.05);(4)After 8 weeks of treatment,there was a statistically significant difference in erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)(P<0.05),indicating that the control group was superior to the treatment group.Conclusion : Toupu Sanhe Lianli Decoction is superior to oral administration in improving abdominal pain,frequent urgency,tenesmus,anorexia,dryness and discomfort,bitter and bad breath,systemic symptoms,emotional ability,social ability,etc.Mesalazine enteric-coated tablets;Mesalazine enteric-coated tablets are superior to oral diaphragm powder and Lianli decoction in improving erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)of spleen-deficiency damp-heat ulcerative colitis There was no significant difference between the two groups in the improvement of ulcerative colitis,submucosal pus and blood,and colonoscopy intestinal mucosa.Therefore,the use of Tori’s method of purifying spleen and removing dampness provides more practical and feasible ideas and methods for clinically guiding the treatment of spleen deficiency,dampness and heat type ulcerative colitis.