| Objective: Through the cohort study,observe the clinical efficacy of the combination of Mongolian and Western medicine in the treatment of bronchial asthma,and compare it with Western medicine treatment alone,to further verify the treatment of Mongolian and Western medicine with therapeutic advantages.Method: In September 2018-December 2018 visits in Inner Mongolia national university hospital in Mongolian medicine and western medicine of respiratory medicine outpatient and the inpatient conforms to the standard of 100 cases of patients with bronchial asthma,were randomly divided into observation group(Mongolian medicine combined treatment group)and control group(western medicine treatment group)and 50 cases each,and one year follow-up.During the follow-up period,the patients were followed up by telephone questionnaires every 3 months(Mongolian medicine total symptom rating scale,assessment of control status questionnaire ACT,asthma quality of life questionnaire Mini AQLQ,control status GINA),and returned to the hospital for follow-up examination every 6 months(FEV1% of lung function,PEF%,Fe NO,EO%,etc.).Record the aggravated hospitalization of the two groups of patients.The lung function FEV1%,PEF%,nitric oxide analysis(Fe NO),eosinophils(EO%),etc.of the two groups before and after treatment were recorded.Finally,using spss22.0 statistical software,the follow-up data of the two groups of patients were statistically analyzed to evaluate the clinical efficacy and value of combined Mongolian and Western medicine in the treatment of bronchial asthma.Results:(1)The total clinical efficacy of the two groups at different times(3,6,9,12months): The total effective rates of observation group were 94%,94%,92%,92%;the total effective rate of the control group were 88%,92 %,88%,86%;no significant difference between the two groups(p> 0.05).(2)Total symptoms of Mongolian medicine:The frequency of morbidity,expectoration and dyspnea were significantly different between the two groups in March(p <0.05);the frequency of morbidity and dyspnea were significantly different between the two groups in December(p <0.05);And there was no significant difference in symptoms between the two groups in June and September(p>0.05).(3)By statistical analysis of the asthma control assessment questionnaire(ACT)at different times,there were significant differences between the two groups before and after treatment;compared between the two groups,there was a significant difference between March and December(both p <0.05)There was no statistical significance between June and September(p> 0.05).(4)By counting the asthma quality of life questionnaire(Mini AQLQ)at different times,there were significant differences between the two groups before and after treatment;compared between the two groups,there were significant differences between March and December(both p <0.05),There was no statistical significance between June and September(p> 0.05).(5)Through statistics on asthma control at different times(GINA),there was statistical significance between the two groups in March(p <0.05),but no statistical significance in June,September and December(p> 0.05).(6)Examination of lung function FEV1% and PEF%: There were significant differences between the two groups before treatment(p> 0.05)in 12 months;there were significant differences between the two groups before and after treatment(p<0.05,p <0.01,p <0.001,,p <0.0001);no significant difference between the two groups(p> 0.05).(7)By observing the examination of exhaled nitric oxide(Fe NO),there was no significant difference between the two groups before treatment(p> 0.05);there were significant differences between the two groups before and after treatment(p <0.01);between the two groups There was no significant difference(p> 0.05).(8)By observing the two groups of eosinophils(EO%),there was no significant difference between the two groups before treatment(p> 0.05);there were significant differences between the two groups before and after treatment(p <0.05,p < 0.01);There was no significant difference between the two groups(p> 0.05).(9)The recurrence rate of asthma in the two groups at different time(3,6,9,12 months): there was no significant difference between the two groups in the third and sixth months(P > 0.05);there was significant difference between the two groups in September and December(all P < 0.05);(10)Hospitalization rate: The hospitalization rate of acute morbidity in the observation group within one year was 16%,and that in the control group was 34%.Conclusion: the efficacy of combination of Mongolian and western medicine in the treatment of bronchial asthma is not significantly different from that of western medicine alone,but the remission time of symptoms is significantly shorter than that of western medicine alone,and it can effectively improve the level of asthma control and quality of life of patients,and reduce the frequency of use of inhaled drugs and the incidence of acute diseases. |
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