Analysis Of 422 Cases Hospitalized Neonatal Mortality In Foshan Women And Children’ Hospital

BackgroundNewborn refers to the infant ligated from the umbilical cord to 28 days after birth,which is the continuation of the fetus.When the transition from the palace to the extrauterine environment,the mortality and morbidity of the newborn are first in person’s life due to the immature development of each organ system.The vast majority of neonatal death reports came from developing countries[3].China is the largest developing country in the world.According to the National Health Committee statistical bulletin,the mortality rate of newborns in 2007-2018 years was 10.7%,10.2%,9%,8.3%,7.8%,6.9%,6.3%,5.9%,5.s4%,4.9%,4.5%and 4.5%respectively,showing a downward trend as a whole.Neonatal mortality is not only one of the important indicators to measure the medical level of a region or even a country,but also one of the important indicators to measure the economic,cultural,maternal and child health care level of the society.Because of the unbalanced development of economy and health care in different regions and hospitals,the neonatal mortality rate is different.A long way to go to reduce neonatal mortality requires the long-term joint efforts of society,government,health care providers,pregnant women and their families.Objective:Investigate the cases of neonatal mortality in Foshan Women and Children’Hospital from January 1,2007 to December 31,2018 retrospectively,analyze the mortality rate,mortality causes of hospitalized neonatal infants and explore the high-risk factors of preterm infant to provide the more scientific basis for reducing the mortality rate of neonatal.Methods1)invetigate and analysis the clinical data of 422 neonatal mortality of Neonatology Department in Foshan Women and Children’ Hospital from January 1,2007 to December 31,2018 retrospectively.2)SPSS 23.0 software to carry out the statistic analysis.The frequency and constituent ratio and rate to indicate the enumeration data,applies x2 to testify the comparison among groups.After screening the relevant factors via single factor analysis,combine with the clinical condition to select the several relevant high-risk factors for preterm,which using the multi-factor logistic regression analysis.P<0.05 is the difference with statistical significance.Results1)There were 35,028 hospitalized neonatal infants from 2007 to 2018,in which 422 neonatal infants are dead after they are born in 28 days with the mortality rate of 1.200.2)In the constitution ratio of neonatal death,the low birth weight infants are 2.20 times more than the normal birth weight infants;the premature-infants are 2.33 times more than the full term infants;the boy infants are 1.67 times more than the girl infants;the early neonatal infants are 4.15 times more than the late neonatal infants.3)The smaller the age the higher the mortality and mortality constitution rate of neonate will be.4)The main mortality causes for the neonatal infants are NRDS(23.9%),neonatal asphyxia(14.7%),birth defect(14.2%),pneumonia/septicemia of neonatal(9.2%),extreme immaturity(8.5%)in sequence.5)NRDS is the top cause for the mortality of premature,low birth weight and early neonatal infants;The neonatal asphyxia and birth defect were retaining in the top three for the mortality causes of neonatal infants.6)The high-risk factors of preterm include:premature rupture of fetal membranes,pregnancy-induced hypertension,pregnancy associated with diabetes,abruptio placentae,gemellary pregnancy,intrauterine infection,hepatitis B virus carrier and cord around neck.Conclusion1.The mortality ratef or hospitalized neonatal infants in our hospital from 2007 to 2018 is 1.20%with the overall situation to demonstrate a downward tendency;The top six mortality causes for neonatal infants were NRDS,neonatal asphyxia,birth defect,pneumonia/septicemia,extreme immaturity in sequence.2.The treatment of low birth age,low birth weight and early newborn is the key to reduce neonatal mortality in this area.3.The important measures to reduce the incidence of premature infants and improve the survival rate are to standardize the examination of labor,find out and deal with the complications of premature rupture of membranes,pregnancy induced hypertension syndrome,pregnancy associated with diabetes,placental abruption,twin pregnancy,intrauterine infection,hepatitis B virus carrier,umbilical cord around the neck and so on.