Study On The Characteristics Of Pulse Chart And Its Correlation With Clinical Classification Of Chronic Urticaria Basing On The Objective Of Pulses Diagnosis

Objective:To explore the relationship between the pulse map of chronic urticaria and its general information?specialized subject?TCM syndrome,it is helpful to understand the value and feasibility of objectifying pulse diagnosis in the population of chronic urticaria,it also can enrich the dialectical elements of chronic urticaria;At the same time,it provides objective reference for the clinical syndrome differentiation of chronic urticaria,so as to establish scientific objectification classification of chronic urticaria from the perspective of traditional Chinese medicine,and provide clinical data for objective study of pulse diagnosis.Methods:The cross-sectional non-intervention study is conducted from January 2019 to December 2019 when the patients out patients in the department of dermatology,affiliated Hospital of Chengdu University of TCM are randomly chosen.Shanghai daosheng DSO1-A tongue surface and pulse information collection system was used to collect pulse images and pulse map parameters of patients,The clinical data were collected by self-made clinical and TCM syndrome information collection form.Chi-square test,one-way ANOVA,independent sample T-test,non-parametric rank sum test were used to analyze the pulse pattern characteristics of chronic urticaria and its correlation with general condition,specialty condition and TCM syndrome type.Results:1.General information and specialized subject of chronic urticariaChronic urticaria was common in young and middle-aged women,and the mean age was 37.43±15.09,the ratio of men to women was 1:2.12;The course of disease ranged from 6 weeks to more than 10 years,with an average of 2.45 ±1.26 years;Most of patients can't locate the etiological of the disease;The onset time is rhythmic,with the night onset was most common,at 21:00 to 23:00 p.m(Hai Shi)or at 19:00 to 21:00 p.m(Xu Shi);The color of the wheal is mainly pink,which is often break out at the trunk and limbs,and often in two or more areas simultaneously,Most patients have higher skin temperature;The UAS scores of the patients were mostly 3-4 points,with an average of 3.72±1.17.2.The pulse chart of chronic urticaria(1)The pulse condition:The pulse position was mainly moderate,accounting for 78.5%.and male patients were mainly moderate and sinking,while that of female patients were moderate and floating.The pulse force was mostly weak,and the pulse rhythm was basically uniform,without knotted pulse and intermittent pulse;The most common pulse condition was wiry pulse and its concurrent pulse,The concurrent pulse mainly include slow-taut pulse,weak-taut pulse,rapid-taut pulse and deep-taut pulse.The differences of single pulse were statistically significant in different gender,age,course of disease,wheal color and wheal location(P<0.01,P<0.05).(2)The pulse chart parameter:The pulse chart parameter values were represented as wiry pulse,there were h3 /h1>0.7,h4 / h1>0.4,h5 / h1<0.05,w1 / t>0.2;The pulse chart parameters were significantly different in different gender,age,etiology and inducement,wheal's color,wheal's location and the severity of the disease.3.The pulse chart parameter and TCM syndrome type(1)The distribution of TCM syndromes :The most common was liver-depression and spleen-deficiency syndrome,the deficiency of both "Qi" and blood,and then the exterior qi's consolidation syndrome,the blood deficiency and wind-dryness syndrome,the blood-stasis syndrome,the endoretention of damp heat and the lung and stomach heat syndrome.(2)There were statistically significant differences in the pulse chart parameter among different TCM syndromes(P<0.01,P<0.05),among them the pulse chart parameters of the blood-stasis syndrome were significantly different from those of other groups;The difference of pulse chart parameters between liver depression and spleen deficiency group and other groups(except blood deficiency and wind dryness syndrome)was statistically significant;There was a significant difference in pulse chart parameters between the lung and stomach heat syndrome group or the endoretention of damp heat and other groups,Excepted for themselves.4.The pulse chart parameter and the excess and deficiency syndromeThere were 116 cases in the excess syndrome group and 65 cases in the deficiency syndrome group(64% and 36% respectively),So chronic urticaria was more common with excess syndrome;The comparison of pulse chart parameters between the excess syndrome group and the deficiency group was statistically significant,they were the values of t3?t5?t?h1?h3?h4?h5?h5/ h1.Conclusion:1.The pulse manifestation and pulse chart parameters of chronic urticaria had a certain rule,and they were significantly correlated with the clinical characteristics of related syndromes of patients,therefore,the objective pulse diagnosis index can be considered as the objective reference index of chronic urticaria.2.The pulse chart parameters of chronic urticaria in different TCM syndromes or syndrome patterns were statistically significant(P<0.01,P<0.05),and there were differences in the pulse chart parameters in different TCM syndromes,which suggests that the objectification of pulse diagnosis and chronic urticaria are worthy of further study.