Analysis Of Postoperative Complications And Clinical Efficacy Of Artificial Joint Replacement In The Treatment Of Hemophilia Arthritis

Objective: To investigate the short-term postoperative complications and clinical efficacy of artificial joint replacement in the treatment of hemophilic arthritis.Methods: A total of 15 patients(5 hips,17 knees)with hemophilic arthritis who underwent artificial replacement from June 2015 to July2018 were included and analyzed retrospectively.Recombinant F ?preparation or virus-inactivated blood-derived F ? preparation was the first choice for coagulation factor replacement therapy of hemophilia type A.virus-inactivated blood-derived prothrombin complex was selected for hemophilia B replacement therapy.HSS score(knee),Harris score(hip),VAS score and target joint bleeding times were followed up after operation.The above score scale scores and joint bleeding times were observed and recorded before and after operation.After discharge,the full-length X-ray films of both lower limbs were reexamined regularly to judge the stability of the prosthesis and the recovery of the joint.Results: The HSS score of patients undergoing knee arthroplasty atthe last follow-up was higher than that before operation(P<0.05),and the difference was statistically significant.The Harris score of the patients undergoing hip arthroplasty at the last follow-up was higher than that before operation(P < 0.05),and the difference was statistically significant.The VAS scores of all patients after operation were lower than those before operation(P<0.05),and the difference was statistically significant.The frequency of target joint bleeding in all patients after operation was lower than that before operation(P < 0.05),and the difference was statistically significant.15 cases(5 hips,17 knees)were followed up for 20.01 ±10.09 months.No periprosthetic infection and fracture occurred in all patients during the follow-up period.1 case had mild hemorrhage in the articular cavity 20 days after left knee arthroplasty,and then formed pseudoaneurysm of popliteal artery of left knee joint.After strengthening the supplement of coagulation factors and proper functional exercise,the incision healed smoothly.Regular postoperative follow-up of the full-length X-ray films of both lower limbs showed that there was no dislocation and loosening of the prosthesis,and the position and force line of the prosthesis were satisfactory.Conclusion: Under the premise of coagulation factor replacement therapy,artificial joint replacement is a reliable choice for patients with end-stage hemophilic arthritis and plays a positive role in reducing pain,improving joint function and improving patients' quality of life.