Risk Factors Of Fetal Growth Restriction In Multiparous Women

Objective: To explore the risk factors of fetal growth restriction(FGR)in reproductive population,so as to provide scientific guidance for reproductive population and improve reproductive quality.Methods: The clinical data of 180 pregnant women who gave birth more than twice in Ningbo Women’s and Children’s Hospital from January 2016 to December 2018 were retrospectively analyzed.According to the presence of FGR(intrauterine growth restriction of fetus),they were divided into FGR group(n=90)and non-FGR group(n=90).The general situation and risk factors of multiparous women in the two groups were analyzed and compared.Independent sample t test,rank sum test,chi-square test,logistic regression were used to statistically process the data by SPSS 21.0 software.Results: The gestational age of FGR group was significantly lower than that of non-FGR group(P<0.05).The weight gain of FGR group was lower than that of non-FGR group(P<0.05).The interval between the last delivery and this delivery in FGR group was longer than that in nonFGR group(P<0.05).There were significant differences.There were no significant differences in age,the number of pregnancy,the number of parturition,and scar uterus between the two groups(P>0.05).The incidence of gestational hypertension in FGR group was significantly higher than that in non-FGR group(P<0.05).The difference was statistically significant.The incidence of placental abnormality,umbilical cord abnormality and oligohydramnios in FGR group was significantly higher than that in non-FGR group(P<0.05).The difference was statistically significant.There was no significant difference in the incidence of gestational diabetes mellitus,hypothyroidism,uterine malformation,ICP,fetal structural malformation,fetal chromosomal abnormality and premature rupture of membranes between the two groups(P<0.05).Logistic stepwise regression analysis indicated that pregnancy-induced hypertension,placental abnormality,umbilical cord abnormality and oligohydramnios were independent risk factors for FGR.Conclusion: Pregnancy hypertension,abnormal placenta,abnormal umbilical cord and oligohydramnios were independent risk factors for FGR in multiparous women.Compared with non-FGR group,FGR group had significantly lower gestational weeks,lower weight gain during pregnancy and longer interval between two deliveries in women who give birth more than twice.Early identification of pregnancy complications,early intervention and treatment,prolonging gestational weeks,providing nutritional guidance during pregnancy,avoiding insufficient weight gain during pregnancy,shortening the interval of reproduction and avoiding old reproduction may reduce the occurrence of fetal growth restriction during reproduction,and ultimately improve the prognosis of newborns.