Analysis Of Related Factors Influencing The Recovery Of Renal Function In Living Related Kidney Transplantation

Objective:To investigate the effects of different donor nephrectomy,vascula anatomy,body mass index(BMI)and donor age on the recovery of renal function in living related kidney transplantation.Method:The clinical data of 416 donors and recipients of living related kidney transplantation from January 1,2009 to January 1,2019 in the second Department of Urology,the first hospital of Jilin University were analyzed retrospectively.The effects of different donor nephrectomy,vascular anatomy abnormality,body mass index,donor age and other factors on the recovery of renal function were compared.Result:From January 1,2009 to January 1,2019,416 pairs of living related donor kidney transplantation were completed in the second Department of Urology,the first hospital of Jilin University.There was no significant difference in blood loss,warm ischemia time,postoperative complications and functional recovery between the two groups(P>0.05),but the operation time of the left donor group was shorter than that of the right donor group(111.4±28.9min v.s.126.0±18min),The difference was statistically significant(P<0.05),among them 306 cases in the single branch group and 110 cases in the multi branch group.There was no significant difference between the two groups in terms of operation time,blood loss,warm ischemia time and recovery of renal function after operation(P>0.05).The difference value between the donor BMI and the recipient BMI(D-R BMI)was positively correlated with the recovery of renal transplantation function.The larger of the difference,the better of the recovery of renal transplantation function.The difference value between the recipient BMI and the donor BMI(R-D BMI)was negatively correlated with the recovery of renal function.The larger of the difference,the worse of the recovery of renal function.The donor's age was negatively correlated with the recovery of renal function.Conclusions:(1)The operation time of retroperitoneal laparoscopic right donor nephrectomy was longer than that of left donor nephrectomy,but the donor side had no effect on the recovery of renal function;(2)Vascular variation of donor renal artery has no effect on the recovery of transplanted renal function;(3)There was a positive correlation between the difference value of D-R BMI and the recovery of renal function,but a negative correlationbetween the difference value of R-D BMI and the recovery of renal function;(4)There was a negative correlation between donor age and the recovery of renal function.