Correlation Between The Ratio Of Neutrophils To Lymphocytes With Essential Hypertension In The Kazakh And Han Nationality In Xinjiang

Objective:To investigate the relationship between neutrophil / lymphocyte ratio(NLR)and Xinjiang Kazakh and Han essential hypertension,and to analyze the relationship between NLR in Xinjiang Kazakh and Han essential hypertension patients Ethnic differences.Methods: The research team conducted an epidemiological survey of hypertension in Hankazitan Township,Manas County,Xinjiang from September 2018 to December 2018,from the population participating in the epidemiological survey,select those aged 18-80,121 cases of Kazakh patients with essential hypertension and 127 cases of Han patients with essential hypertension were taken as the case group,at the same time choose healthy people of the same ethnicity and age,108 Kazakhs and 106 Hans were used as the normal control group.The general clinical data of the study subjects were recorded.All the enrollees took forearm venous blood to detect blood routine and biochemical indicators,and calculate NLR values.SPSS 17.0 statistical software was used for analysis.`x±swas used to represent the measurement data of the normal distribution.The t test was used to compare the two groups of means.The c2 test was used to compare the count data.The multivariate logistic regression analysis was used to analyze the Kazakh and Han ethnic groups in Xinjiang.Independent risk factors for hypertension.P <0.05 was used as the inspection level.Results:(1)Compared with the control group,Xinjiang Kazakh and Han ethnic groups had higher NLR values(P <0.05).(2)The level of NLR in the Kazakh primary hypertension group in Xinjiang was higher than that in the Han primary hypertension group(P <0.05).(3)Univariate logistic regression analysis was performed and found that the main risk factors for essential hypertension in Xinjiang Kazakh and Han nationalities include patient age,waist circumference,BMI,fasting blood glucose value,NLR value,triglyceride level,total cholesterol level,and low density lipoprotein Cholesterol level,creatinine and urea nitrogen,(P <0.05);albumin and high-density lipoprotein cholesterol values are the main protective factors(P <0.05).(4)Multivariate logistic regression analysis found that the independent risk factors for the development of essential hypertension in Kazakh and Han nationalities in Xinjiang were patient NLR value,LDL cholesterol,and urea nitrogen indicators;and NLR was independent of traditional risk factors,and was independent of Xinjiang Kazakh and Han people are independently related to essential hypertension,P= 0.002,OR 2.355 95%CI(1.367~4.058).Conclusions:(1)NLR is associated with the incidence of essential hypertension in Kazakhs and Hans in Xinjiang.(2)There are ethnic differences in NLR among Xinjiang Kazakh and Han people with essential hypertension.