| Objective:To discuss the clinical features of bilateral acute cerebral infarction.Methods:Medical records of 696 cases with first acute cerebral infarction who were hospitalized in the department of neurology of the first affiliated hospital of Nanchang university from January 2017 to December 2019 were collected,wherein348 cases with bilateral acute cerebral infarction(BACI)were divided into an experimental group,and 348 cases with unilateral acute cerebral infarction(UACI)who were hospitalized in the same period were randomly selected and divided into a control group.The data of the two groups were collected,including age,gender,National Institutes Of Health Stroke Scale(NIHSS)score on admission,modified Rankin Scale(mRS)score on admission,body mass index(BMI),drinking,smoking history,serum homocysteine,anemia,blood lipid,diabetes,atrial fibrillation,other cardiac histories,hypertension,magnetic resonance imaging(MRI),magnetic resonance angiography(MRA)and so on.The above data were summarized and statistically analyzed.Results:1.Of all the cases in the BACI group,236(67.8%)were male and 112(32.2%)were female,with onset age from 19 to 94;and the median and interquartile distance of onset age were 65(56.5,73.5).In the UACI group,203(58.3%)cases were male and 145(41.7%)cases were female,with onset age from 22 to 92;and the median and interquartile distance of onset age were 63(55,70).The onset age and the incidence of male in BACI group were higher than those in UACI group(P<0.05).2.The NIHSS score on admission in the BACI group was higher(P=0.000<0.05),which indicated that the neurological deficit of BACI was more serious when entering hospital.The differences in smoking history(?~2=7.113,P=0.008),dyslipidemia(?~2=18.018,P=0.000),diabetes mellitus(?~2=14.449,P=0.000)and atrial fibrillation(?~2=9.464,P=0.002)were statistically significant between the two groups.The proportion of the risk factors,such as smoking history,dyslipidemia,diabetes mellitus and atrial fibrillation,in BACI group was higher than that in the UACI group.No statistical significance was showed between the two groups in overweight and obesity(?~2=2.953,P=0.086),intracranial vascular stenosis or occlusion(?~2=1.480,P=0.224),drinking(?~2=0.378,P=0.539),hyperhomocysteinemia(?~2=0.042,P=0.838),hypertension(?~2=1.870,P=0.172),anemia(?~2=2.478,P=0.115),heart diseases(except atrial fibrillation)(?~2=1.133,P=0.287)and mRS score on admission(?~2=4.554,P=0.103)(P>0.05).3.The proportion of BACI patients in the posterior circulation group and the anterior and posterior circulation group was higher than that of UACI patients;the proportion of UACI patients in the anterior circulation group was higher than that of BACI patients.4.The frequency and percentage of stroke of undetermined cause,cardioem-bolism and stroke of other determined cause in the BACI group were higher than those in the UACI group.The frequency of percentage of small-artery occlusion in the UACI group were higher than those in the BACI group.Large artery atherosclerosis was the most common type of cerebral infarction in the two groups.Conclusions:1.Compared with UACI patients,the onset age and the incidence of male of BACI patients were higher.2.Compared with UACI patients,the BACI patients had higher NIHSS score when entering hospital,and the neurological deficit was more serious.3.The proportion of the risk factors,such as dyslipidemia,smoking,diabetes mellitus and atrial fibrillation,in the BACI group was higher than that in the UACI group.4.Compared with the UACI,the posterior circulation group and the anterior and posterior circulation group in BACI were involved more easily,and the anterior circulation group in BACI was involved less.5.Large artery atherosclerosis was the most common type in BACI.Stroke of undetermined cause,cardioembolism and stroke of other determined cause in the BACI group were higher than those in the UACI group,whilst small-artery occlusion in the UACI group was higher than that in the BACI group. |
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