The Quality Standards Of Dendrobium Candidum Are Improved And The Quality Comparison Of Products With Different Processing Methods

Dendrobium medicinal materials contained in?Chinese Pharmacopoeia?2015 edition,the main efficacy:Nourishing Yin and clearing heat,benefiting stomach.In recent years,a wide range of applications,but by preliminary investigation:most Medicinal Dendrobium in the ratio of mannose and glucose peak area does not conform to the Pharmacopoeia,the associated with the standard drafting unit of communication that,in the formulation of the standard at the beginning,due to sample size leads to a standard limit setting is not reasonable,there are some defects,which seriously restrict the development of Dendrobium candidum industry,so the extensive market research and evaluate the quality of Dendrobium commodity circulation,develop a reasonable quality standard of Dendrobium candidum And the healthy development of the Dendrobium candidum industry chain,has important significance.This paper collected in different producing areas of Dendrobium 104 batches of medicinal materials,the comparative study of the quality,according to the research results:the reasonable limits of mannose and glucose peak area ratio;the other found in the comparative study of quality of Dendrobium and mannose determination of polysaccharide content in the pretreatment time is too long,the process is complex and need expensive reagents,resulting in high testing cost,and specificity is poor.According to reports in the literature:naringenin as specific ingredients in Dendrobium candidum with anti-inflammatory,antibacterial,analgesic,antioxidant,anti-tumor and immune Regulation effect,determination reagent naringenin need low price,and the method is rapid,accurate,reliable,therefore,intends to increase the determination of Dendrobium as control quality index of content in the peel,in order to better control the quality of Dendrobium medicinal materials and related products.According to the research results:the proposed amendment to the?Chinese Pharmacopoeia?2015 version of Dendrobium standards to the National Pharmacopoeia Committee and the Guizhou provincial food and drug administration proposed amendments to Guizhou province"Chinese herbal medicine,National Medicinal Dendrobium(Ganoderma powder,lyophilized)" quality standard;and the different parts,different processing methods of the quality system of Dendrobium candidum Comparative study.Dendrobium root belongs to the aerial roots of Dendrobium,often epiphytic or in pine rock matrix,artificial imitation of the wild in the pine bark,due to the large number of cutting pine for pine bark,which caused serious damage to the natural environment;Polygonum capitatum belongs to whole plant medicine,will produce a large number of Polygonum capitatum dregs in this experiment,Polygonum capitatum and pine bark in different proportion of cultivated Dendrobium,this study will solve the waste dregs of Polygonum capitatum pharmaceutical waste recycling,reduce environmental pollution residue,but also reduce the ecological damage caused by the felling of pine trees.1 Dendrobium candidum and improve the quality standard of amendment1.1 Comparative study of Dendrobium candidum quality in different regionsBased on the 104 different areas(Zhejiang,Yunnan,Guizhou,Jiangsu)Comparative Study on quality of Dendrobium Ironhide,according to the experimental results indicated that:104 different batches of Dendrobium officinale mannose content of the qualified rate is 84.6%,49 different batches of Dendrobium officinale polysaccharide content of the qualified rate is 77.6%,the origin and the level similar to the mannose content of polysaccharide,demonstration the formulation of the 2015 edition of?Chinese Pharmacopoeia?Dendrobium polysaccharide content limits the rationality of.104 group of different origin of Dendrobium candidum mannose and glucose peak area ratio of the qualified rate is 36.5%,the unqualified rate was 63.5%,from the production point of view:Zhejiang Jiang,Yunnan,Guizhou,Dendrobium mannose and glucose peak area ratio of Jiangsu origin of the unqualified rate were 53.1%,58.8%,76.5%,100%;it can be judged for the 2015 edition of?Chinese Pharmacopoeia?of Dendrobium under the peak area ratio of mannose and glucose standard limit is too high,resulting in most of mannose and glucose peak area ratio is not qualified.Based on 104 different batches of the main origin of commercially available Medicinal Dendrobium candidum analysis:mannose and glucose peak area ratio of the average value is 2.3,the ratio of 1.84.to fall 20%in combination with the production practice,suggestions:2015 edition?Chinese Pharmacopoeia?Dendrobium under "mannose and glucose peak area ratio limit by" 2.4?8 "revised as " 1.8 to 8".1.2 A comparative study of different origin of Dendrobium naringenin content Based on the 15 different areas(Zhejiang,Yunnan,Guizhou)a comparative study on the content of Dendrobium naringin,according to the experimental results indicated that:the average content from the origin point of view,Zhejiang,Yunnan,Guizhou origin of naringenin average contents were 13.19%,13.6%,10.59%,the mannose and glucose peak area than the corresponding average value 2.61,2.46,1.94.were:Zhejiang,Yunnan origin of the average content of naringenin and mannose and glucose similar peak area than the average,higher than the Guizhou origin;it can be concluded that the average content of Dendrobium naringenin and mannose and glucose The correlation between the peak area ratio and the average value can be preliminarily judged as one of the indexes for quality control of Dendrobium candidum.2 A comparative study on the quality of products of different processing methods 2.1Comparative study on the quality of broken wall and broken wall Dendrobium candidumThe 12 group before and after breaking a comparative study on the quality of Dendrobium,according to the experimental results indicated that:the mannose and polysaccharide content as the index,the quality of Dendrobium candidum wall after wall quality is better than before.Through the analysis of the 12 batch of Dendrobium candidum wall powder test results:mannose and glucose peak area ratio of the average value is 1.87,the ratio of 1.5.to fall 20%in combination with the production practice,suggestions:<Chinese medicine in Guizhou Province,the national standard of Dendrobium candidum medicine Yinpian>cell broken powder under the mannose and glucose peak area ratio limit from "2.4 to 8" revised as "1.5 to 8".2.2Comparative study on quality of Dendrobium candidum with different particle size The different particle size of 5 batches(50100200400500800 mesh)Comparative Study on quality of Dendrobium Ironhide,according to the experimental results of different particle size,with the decrease of particle size is also increased the dissolution of active ingredients in Dendrobium;common powder of 100 mesh and mannose in the glucose peak area ratio,mannose and polysaccharide content reached the maximum wall powder 400 mesh in the mannose and glucose peak area ratio,mannose and polysaccharide content reached the maximum value.Considering the Dendrobium ordinary powder particle size is 100 mesh quality best;broken powder particle size is 400 mesh The best quality.2.3Comparative study on quality of Dendrobium candidum with different drying methodsThe 15 batch of different drying methods(freeze-drying,drying)Comparative Study on quality of Dendrobium Ironhide,according to the experimental results indicated that:the mannose and polysaccharide content as index,the quality of Dendrobium freeze-dried powder is better than the quality of drying powder.Through the analysis of test results of 15 batches of frozen dried Dendrobium:mannose and glucose peak area ratio of the average value is 1.07,the ratio of 0.86.to fall 20%in combination with the production practice,suggestions:<Chinese medicine in Guizhou Province,the national standard of Dendrobium candidum medicine Yinpian>freeze-dried powder under the dew sugar and glucose peak area ratio limit by "2.4?8" revised as "0.9 to 8".3 Dendrobium candidum with different commercial grades and recycling3.1 Comparative study on different parts of the quality of Dendrobium candidumThe 15 batch of Dendrobium candidum in different parts(top,middle and bottom section,full bead,leaves,flowers)a comparative study on the quality,according to the experimental results indicated that:the ratio of mannose and glucose peak area were determined as follows:the quality of the various parts of the bottom section>the top section>Middle part>all beads;with mannose content as the index,the quality of each part as follows:Bottom section?5 middle section ? full bead>top segment;and the content of polysaccharide as the index,the quality of each part as follows:Bottom section ? full bead>middle section>top segment;according to the three indexes into consideration,all parts of which the quality of Dendrobium candidum as follows:Bottom section>middle section ? full bead>top segment.So the whole Pearl River,tin In the bottom of a fresh Dendrobium,as a commodity,the middle class two goods,the top section is three grade goods.Shi Huye also contains iron and mannose and polysaccharide of dendrobium stem and leaves and flowers that have the same medicinal value.3.2Comparative study on quality of Dendrobium planting different iron matrixAccording to the different matrix(Polygonum capitatum,pine bark)a comparative study on the quality of Dendrobium planting,according to the experimental results indicated that:different proportions of Polygonum capitatum dregs and pine bark cultivation of Dendrobium a fresh water,the ratio of mannose and glucose peak area,mannose content and polysaccharide content of the results are very similar,can determine the initial drug factory the waste residue of Polygonum capitatum using waste can replace the pine bark cultivation of Dendrobium candidum,How to replace need further study.