Correlative Study On Changes Of Impulse Cardiogram And Evaluation Of Curative Effect After Angina Pectoris With Different TCM Syndromes

Coronary atherosclerotic heart disease is the most common disease in the human cardiovascular system with the characteristics of the high incidence and high mortality,seriously threatening human health.In recent years,the development of interventional techniques has greatly reduced the mortality of patients with coronary heart disease.However,interventional treatment only solves the stenosis of criminal vessels,and can not fundamentally reverse the process of atherosclerosis.Therefore,early prevention and treatment is significant for the occurrence and development of coronary heart disease.Ballistocardiogram(BCG)is a new testing instrument in the field of medical physics.Pro.Cao Xinrong in Tsinghua University and others preliminary find that there are significant differences in the characteristics of BCG between the preoperative patients with coronary heart disease and the postoperative ones.Inan et al.compared the BCG signal before and after cardiac resynchronization therapy,finding that the patient's cardiac functions improve after treatment,and the IJ amplitude of BCG increased.Two studies have initially found that the BCG has the possibility to evaluate the therapeutic effect of coronary heart disease,but there is still no supporting evidence.Based on this,in this study,the BCG of patients with coronary heart disease and angina before and after stenting were collected,and the differences of characteristics of BCG before and after the stenting were analyzed to explore their possibility of evaluating the therapeutic effects of coronary heart disease;the previous studies of this subject have confirmed the correlation between BCG on different syndromes of coronary heart disease with congestive heart failure and coronary heart disease with angina pectoris.In this study,the characteristics of BCG before PCI of patients with angina of various types of TCM syndromes are analyzed to explore the possibility of applying BCG into TCM differentiation.Purposes1.To analyze and compare the characteristic interval and the changing laws of amplitude of BCG before and after PCI of coronary heart disease with angina pectoris,and explore the possibility of evaluating the therapeutic effects of coronary heart disease with angina pectoris;2.To analyze the characteristics of BCG of different TCM syndromes of coronary heart disease with angina pectoris,and explore the objective basis for syndrome differentiation of TCM;MethodFrom January 2018 to March 2019,,the eighty-one patients with coronary heart disease after PCI who had admitted in Dongfang Hospital were enrolled in the present study.The patients was divided into pre-stenting group of coronary heart disease with angina pectoris and post-stenting group of coronary heart disease with angina pectoris,which then according to the syndrome types,were divided into five sub-groups,including deficiency of both qi and yin group,qi deficiency and blood stasis group,qi stagnation and blood stasis group,stagnant blockade of heart blood group,heart and blood stasis group,and phlegm obstructing the heart vessels group.The diagnostic criteria for Western medicine are based on The Naming and Diagnostic Criteria for Ischemic Heart Disease developed by the International Society of Cardiology in 1979 and WHO and the examination results of coronary angiogram.The syndrome differentiation of TCM is based on the Guiding Principles for Clinical Study of New Chinese Medicines issued by National Medical Products Administration in 2002,and the author of this paper collected the BCG data 24 hours before and 48 hours after PCI of the 81 patients enrolled in the study,with the main indicators of the BCG as HI,IJ,JK amplitude and their interval tHI,tIJ,tUK,tRJ.All data were statistically analyzed by SPSS20.0.The count data were analyzed by chi-square test,the grade data were analyzed by rank sum test,the measurement data were analyzed by t test,analysis of variance or non-parametric test,and the correlation was analyzed by Spearman.The admission and reject value was P<0.05.Results1.There were significant differences in tIJ,tRI and tRJ between the pre-stenting group and the post-stenting group of patients with coronary heart disease with angina pectoris,P<0.05,with statistical difference;2.There were significant differences in the amplitudes of HI,IJ and JK of BCG between pre-stenting group and the post-stenting group of patients with coronary heart disease with angina pectoris,P<0.05,with statistical difference;3.There were significant differences in the IJ interval of the TCM syndromes of all the enrolled patients,P<0.05,with statistical difference;4.There were significant differences in gender distribution among the enrolled patients,and the male were the majority(P<0.05);There were no significant differences in age between the enrolled male and female(P>0.05).5.Among the enrolled patients,the lesion of male patients came more complicated than that of the female patients,with more single-vessel lesions of female.The double-vessel and triple-vessel lesions of male were more than those of female.Conclusions1.There are significant differences in the main indicators of tIJ,tRI,tRJ and HI,IJ and JK amplitude of BCG before and after PCI,which can be used as an index to evaluate the therapeutic effect of coronary heart disease;2.There are significant differences in the IJ interval of patients of five TCM syndrome with coronary heart disease before PCI,which can provide objective quantitative basis for syndrome differentiation of TCM.