Research On TCM Syndromes Of Rheumatoid Arthritis With Anemia

Objective: In this retrospective study,115 patients with RA complicated with anemia were studied to investigate the distribution of TCM syndromes and the correlation between syndromes and patients’ general information,symptoms and signs,and laboratory examinations.Methods:A retrospective study was conducted to select RA patients with anemia who met the inclusion criteria from January 2018 to December 2018 in the Department of Rheumatology and Immunology,Affiliated Hospital of Liaoning University of Traditional Chinese Medicine.General data(including gender,age,duration of disease),TCM data(including TCM diagnosis,syndromes,tongue coating,pulse signs),symptoms and signs(including joint swelling,joint tenderness,joint deformities,morning stiffness time),laboratory data(including Hb,RBC,RF,CCP,ESR,CRP,IgA,IgG,IgM),DAS28 score,VAS score,etc.)were collected.Data,establish a database,and use statistical methods to analyze and summarize,draw conclusions.Results:1.Among the patients participating in the survey,in terms of disease position,the most common syndrome differentiation of TCM is heart syndrome,followed by kidney syndrome and pulmonary syndrome;in the double-position syndrome,the most common combination is cardiopulmonary syndrome,followed by It is a liver and kidney syndrome;the most common combination of the three disease syndromes is cardiopulmonary syndrome.2.In terms of the patient’s pathological syndrome,the most common syndrome differentiation of Chinese medicine is phlegm,followed by qi deficiency and blood stasis;among them,the three most common combinations are qi deficiency,blood deficiency and yin deficiency;The most common type of disease combination is qi deficiency and yin deficiency;the most common symptoms of wind syndrome,cold syndrome,phlegm and blood stasis.3.There was no significant correlation between the disease syndrome and the number of joint swelling,joint tenderness,joint deformity and morning stiffness.4.There is a significant correlation between pathogenic syndrome and Hb,RBC,CRP and ESR.5.There was no significant correlation between pathogenic syndrome and IgA,IgG,IgM,and RF,and there was a significant statistical difference between the anti-CCP and anti-CCP antibodies.6.There was no correlation between the disease syndrome and the DAS28 score,and there was a statistically significant difference from the VAS score.Conclusion:1.Among the patients with RA complicated with anemia,the symptoms of disease location are more manifested in heart,kidney and lung,while the symptoms of disease nature are more manifested in phlegm-dampness,Qi deficiency and blood stasis.2.Hb is correlated with pathogenic syndrome elements,especially in patients with heat,blood deficiency and phlegm-yin syndrome elements.3.ESR and CRP are correlated with pathogenic syndrome elements,among which patients with cold syndrome,Fire-heat syndrome,Yang deficiency syndrome and wind syndrome have higher disease activity.4.Anti-CCP antibody was correlated with the activity of venereal syndrome elements,and the anti-CCP antibody increased significantly in patients with blood stasis,cold syndrome and heat syndrome.5.DAS28 score is closely related to the patient’s type of syndrome,the performance of cold syndrome,fiery,dampness,blood stasis and other DAS28 score higher.