| Objective:This paper is based on the TCM theory of "the five spirits",according to professor Teng Jing and her many years experience,it is found that disorder of five spirits caused by psychological and emotional factors is the main pathogenesis of insomnia.Especially the symptoms of hyperactivity of Hun and deficiency of Po are the most common.It is found that Dinghun Yipo Decoction has a good effect in treating insomnia.The clinical efficacy of insomnia and the improvement of TCM syndromes are expected to establish a system of differentiation and treatment of insomnia based on the integration of body and spirits.Methods:Sixty insomniacs were selected from the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from December 2017 to December 2018.They were randomly divided into experimental group and control group with 30 cases in each group.The experimental group was given Dinghun Yipo Decoction(gastrodia elata 12 g,amber powder(take after mixing it with water)1g,raw keel 15 g,white peony 12 g,raw liquorice 6g,ginseng 12g(single package),Angelica 12 g,winter 12 g,Fushen 15 g,Yuanzhi12g,etc.Fangfeng 12 g,Muxiang 12g)combined with zopiclone tablets(trade name:Sanchen;manufacturer: Qilu Pharmaceutical Co.,Ltd;specification: 7.5mg * 12 tablets;approval number: Chinese medicine standard H10980163)treatment,the control group was treated with zopiclone tablets,the treatment cycle was 28 days,and before and after treatment,respectively,filled in the self-made Chinese medicine five spirits strength and weakness scale and Pittsburgh Sleep Quality Index(PSQI)quantity.Tables were used to evaluate the sleep quality of patients and the improvement of Pentathlon Syndrome.Clinical data were collected after the treatment cycle.Statistical software SPSS 22.0 wasused to analyze the data and draw conclusions.Results:1.There was no significant difference in sex,age,and course of illness(P>0.05)between the two groups of general data and it was comparable.2.Clinical efficacy determination:clinical efficacy: control group total 30 cases,clinical cure 1 case,excellent effective 7 cases,effective 14 cases,invalid 8 cases,total effective 73.33 %.The total number of experimental groups was 30,3 clinical cures,18 excellent effective,6 effective,3 ineffective,and the total effective rate was 90.00 %.The clinical efficiency of the experimental group was significantly higher than that of the control group(P<0.05).3.Determination of the curative effect of traditional Chinese medicine:(1)control group total of 30 cases,clinical cure 1 case,excellent effective 6 cases,effective 12 cases,invalid 11 cases,total effective rate 63.33 %;In the experimental group,30 cases were effective,4 were clinically cured,14 were excellent effective,8 were effective,4 were ineffective,and the total effective rate was 86.67 %;The clinical efficiency of the experimental group was significantly higher than that of the control group(P<0.05).(2)Chinese medicine syndrome total score and various components: The test group in the total score and improvement of the rib swelling pain and discomfort,many dreams,heart anxiety,panic,slow language,Low speech,memory of recent events,shortness of breath,weakness of the body muscles,and recall of what has just been said or done are significantly superior to the control group(P<0.05).But there is no significant difference between people in nightmares at night,difficultly sleep at night or even awake all night,light sleep,blurred vision,and hearing loss,can’t hear other people’s speech,speak unclear words,rough skin,and nasal congestion(P>0.05).4.Pittsburgh Sleep Quality Index,PSQI Improvement:(1)Clinical efficacy: 30 cases in the control group,1 case was clinically cured,8 cases were excellent effective,15 cases were effective,6 cases were ineffective,total effective is 80 %;30 cases in the experimental group,4 cases were clinically cured,12 cases were excellent effective,10 cases were effective,4 cases were ineffective,and the total effective rate was 86.67 %;The clinical efficiency of the experimental group was significantly higher than that of the control group(P<0.05).(2)PSQI total score and each component: The experimental group was better than the control group(P < 0.05)in terms of total score and improvement of sleep time,sleep quality,sleep efficiency,daytime dysfunction,and total score.There wasno significant difference in sleep time,sleep disorder,and hypnotic drugs(P>0.05).Conclusion : 1.Compared with the control group,the experimental group has a remarkable effect in improving the total effective rate of insomnia of hyperactivity of Hun and deficiency of Po type.2.Compared with the control group,the total effective rate of TCM treatment and the total score of TCM syndromes in the experimental group and part of syndromes were higher than those in the control group.3.The control group and the experimental group have obvious therapeutic effect on PSQI total score and some factors of insomnia.4.To sum up,Dinghun Yipo Decoction has a good therapeutic effect in the treatment of insomnia of hyperactivity of Hun and deficiency of Po,and its combined application with Zopiclone tablets has achieved remarkable clinical efficacy,which is worthy of promotion and application. |
PDF Full Text Request