| Objective:This paper discusses the effect of invigorating qi and activating blood on T2DM by observing clinical trials and animal experiments.Meanwhile,the paper further explores the best ratio of the classic drugs of invigorating qi and activating blood(astragalus membranaceus and angelica sinensis,Qigui).Methods:Clinical observation:We randomly divided 70 patients with T2DM into experimental group(30 patients)and control group(30 patients).The two groups were given the same basic treatment.And the experimental group was treated with traditional Chinese medicine(TCM)of invigorating qi and activating blood.The clinical observation time is 8 weeks.Animal experiment:We randomly divided 60 SD rats into normal control group(10 rats)and the creation model group(50 rats).After creating a type 2 diabetes model successfully,we randdomly divided the rats into model group,3 different Qigui couplet medicine groups(1:1,3:2,5:1)and western medicine group.Each group was treated with placebo,Chinese medicine and western medicine by gavage.And the gavage time is 8 weeks.Results:Clinical observation:the method of invigorating qi and activating blood circulation in the treatment of type 2 diabetes was better than the control group in the improvement of glucose and lipid metabolism disorder,insulin resistance and TCM syndromes(P<0.05).Animal experiments:each group of the ratio of Qigui couplet medicine had certain improvement in the rats with T2DM(P<0.05).And the performance of Qigui couplet medicine group 5:1 and 1:1 was better than that of 3:2(P<0.05).Conclusion:The method of invigorating qi and activating blood circulation had a good improvement effect on TCM syndromes and related blood indicators in type 2 diabetes.And the best curative effect of type 2 diabetes is the Qigui couplet medicine group 1:1 and 5:1. |
PDF Full Text Request