Clinical Intervention Study Of TCM Health Management Mode Based On Differentiation And Treatment With Constitution On Non-Alcoholic Fatty Liver Disease With Hlegm-Dampness

Objective:Patients with phlegm-dampness NAFLD were evaluated,intervened and managed by the TCM health management mode based on the principle of body differentiation and treatment.To observe the therapeutic effect of TCM health management mode based on the principle of body differentiation on patients with phlegm-dampness NAFLD.Methods:In this study,a randomized controlled trial was used to randomly divide 80 patients with phlegm-dampness NAFLD who met the inclusion criteria into a TCM health management group and a Western medicine treatment group.TCM health management group Implement the management scheme of traditional Chinese medicine decoction(Zaozhu Erchen fang)with ear points(liver,spleen,stomach,kidney,Sanjiao)combined with medicatedl diet(semen coicis,dioscorea opposita,semen nelumbinis),western medicine treatment group use polyene phosphatidylcholine capsules treatment,at the same time two groups of patients were given diet movement instruction,course of 24 weeks.Liver function(ALT,AST,GGT),blood lipid(TC,TG,LDL-C,HDL-C),BMI,CAP,LSM,color Doppler classification of fatty liver,phlegm-dampness constitution score,quality of life score of the patients were observed,and the efficacy of the two groups was compared.Results:Thirty-eight patients with phlegm-dampness NAFLD in the TCM health management group and the Western medicine treatment group each completed the entire course of treatment.Compared with before and after treatment,ALT,AST,GGT,TC,TG,HDL-C,BMI,CAP,LSM,phlegm-dampness constitution score and quality of life score in TCM health management group were significantly improved,with statistical significance(P<0.05),while there was no statistical significance in LDL-C before and after treatment(P>0.05).ALT,AST,GGT,TC,TG,HDL-C,BMI,CAP and LSM of patients in the western medicine treatment group were improved before and after treatment,with statistical significance(P<0.05).There were no significant differences in LDL-C and phlegm-dampness constitution scores compared with those before treatment(P>0.05).There was no significant difference in liver function(ALT,AST,GGT),blood lipid(TC,TG,LDL-C,HDL-C),CAP,LSM,quality of life score and phlegm and dampness constitution score between the two groups before treatment(P>0.05),which showed comparability.After treatment,the total effective rate of the TCM health management group was 92.11%,and the total effective rate of the western medicine treatment group was 86.84%,with no statistical significance(P>0.05).There was no significant difference in liver fat content between the two groups(P>0.05).The effective rate of improvement of phlegm and dampness constitution in the TCM health management group was 86.8%,and that in the western medicine treatment group was 5.3%.The effective rate of improvement of phlegm and dampness constitution in the TCM health management group was better than that in the western medicine treatment group,the difference was statistically significant(P<0.05).After treatment,ALT,AST,GGT,TG,LDL-C,HDL-C,BMI and LSM were not significantly different between the two groups(P >0.05),while TC,CAP,quality of life score and phlegm and dampness constitution score in the TCM health management group were lower than those in the western medicine treatment group,with statistical significance(P<0.05).Conclusion:After 24 weeks of intervention,liver function,blood lipid,BMI,CAP,LSM,phlegm and dampness constitution and quality of life indexes in the TCM health management group were significantly improved compared with those before treatment,with a total effective rate of92.11%,and the improvement of TC,CAP,quality of life and phlegm and dampness constitution indexes was significantly better than that in the western medicine treatment group.The TCM health management mode based on the principle of body differentiation and treatment can better reduce the liver fat content and cholesterol level of NAFLD patients,and has a better effect on the improvement of patients’ constitution and quality of life.It is a better treatment mode and worthy of further promotion and application.