| Objective: The purpose of this study is to use the folk prescription(potato + alum + borneol)to evaluate the clinical efficacy of Xiaoding ointment in the treatment of knee joint traumatic synovitis and to provide a new choice for the treatment of knee joint traumatic synovitis.Methods: From June 2020 to January 2021,90 patients with knee traumatic synovitis in the outpatient clinic of the second people’s Hospital of province were arbitrarily divid ed into 2 teams.45 patients within the experimental cluster were treated with folk prescrip tion(potato+alum+borneol),once a day,externally applied;covering the swollen joint,t he thickness was about 2mm,and the course of treatment was 2 weeks.The control group(45cases)was treated with Xiaoding ointment,once a day,applied externally,co vering the swollen joint,the thickness was about 2mm,and the course of treatment w as 2 weeks.The VAS score,WOMAC score,knee swelling degree and overall curativ e effect of the two groups were observed before and after treatment.Changes in the l evels of IL-1β,IL-6 and TNF-α in body fluids before treatment,one week of treatme nt and two weeks of treatment were measured by enzyme-linked immunosorbent assay.All the clinical data were statistically analyzed by SPSS23.0 software to evaluate the clinical efficacy of folk prescription(potato+alum+borneol)in the treatment of knee joi nt traumatic synovitis.Results: A total of 90 patients with traumatic synovitis of knee joint were included in this study.The experimental group included 45 cases and dropped out in 7 cases,of which 3 cases withdrew voluntarily because of unsatisfactory treatment effect,3 cases lost follow-up,1 case received other drug treatment midway,and finally 38 cases were counted.35 cases were included in the control group,5 cases withdrew voluntarily due to personal reasons,3 cases could not insist on treatment,and 2 cases received other drug treatment.1.Comparison of VAS scores: The variations were statistically important once compariso n the intra-group VAS uncountable the 2 teams of patients before and when treatment(P<0.05);the variations weren’t statistically important once comparison the inter-group compa rison of the 2 teams of patients after treatment(P>0.05).2.Comparison of overall WOMAC ratings:there was vital distinction within the total score of WOMAC between the 2 teams before and when treatment(P<0.05),and between the2 teams before and when treatment(P<0.05).3.Comparison of knee swelling degree: there was vital distinction in knee membrane thick ness between the 2 teams before and when treatment(P<0.05),and between the 2 teams b efore and when treatment(P<0.05).4.Comparison of overall efficacy evaluation: before and after treatment,The total effective rate of the trial cluster reached eighty nine and also the total effective rate of the management cluster reached eighty three.the treatment result of the take a look at cluster was higher.5.Comparison of the content of IL-1β in serum:there was vital distinction within the co ntent of IL-1β between the 2 teams once one week treatment(P<0.05),however there was no vital distinction within the content of IL-1β in a pair of weeks treatment group(P>0.05),and there was significant difference between the two groups after 1 week treatment and 2 weeks treatment(P<0.05).6.Comparison of serum IL-6 content: there was vital distinction in IL-6 content betwee n the 2 teams once one week and a couple of weeks treatment(P<0.05),however there w as no vital distinction between the 2 teams once one week and acouple of weeks treatment(P>0.05).7.Comparison of the content of TNF-α in serum: there was significant difference in the content of TNF-α between the two groups after 1 week and 2 weeks of treatment(P<0.05),and between the two groups after 1 week and 2 weeks of treatment(P<0.05). |
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