| Objective: To investigate the status and risk factors of Helicobacter pylori(Hp)infection in preschoolers in Youjiang District of Baise,in order to provide active and effective measures to prevent the infection of Hp in children.So as to reduce the Hp infection rate of children in this area.Methods: A stratified random sampling of 350 preschoolers from six kindergartens in Youjiang District by grade was taken as the research object.With the informed and agreed of the parents,basic information such as gender,age,ethnicity,height and weight of the children,feces of the children,venous blood of part of the parents and a questionnaire survey were collected.The fecal Hp antigen test(Hp SA)was used to detect whether the children were infected with Hp,and the serum Hp antibody test was used to detect whether the parents were infected with Hp.Data on risk factors were collected by telephone online questionnaire survey,which included children’s general information,children’s living and health habits,parents’ general personal information,parents’ personal and maintenance habits,family health environment,family economic situation and parents’ understanding of Helicobacter pylori,etc.(See Annex 1 for details).Using single factor analysis of X2inspection to the independent variable,and have significant difference on the single factor analysis statistically significant independent variables multivariable Logistic regression analysis.Results:(1)A total of 321 preschoolers in Baise Youjiang District completed the survey,among which 83 were positive and 238 were negative.The infection rate of Hp was25.86%.(2)There was no statistical difference in the infection rate of Hp among different genders(P>0.05);The infection rate of Hp in different age groups was statistically significant(P<0.05);There was no significant difference in Hp infection rate among different nationalities(P>0.05).(3)There were no statistically significant differences in height and weight between the Hp positive and negative groups(P>0.05).(4)Hp infection in children is associated with Hp infection in parents(P<0.05).(5)Univariate analysis showed that Hp infection was related to finger sucking and toys,tooth brushing in the morning and evening,hand washing before eating and after defecating,sharing tableware and drinking cups with parents,liking cold drinks,eating out,feeding after chewing,and parents’ knowledge of Hp.The difference was statistically significant(P<0.05).(6)Logistic regression analysis showed that age(OR=2.042,95%CI:1.41～2.96,P<0.001),finger sucking and toy sucking(OR=8.225,95%CI:3.67～18.59,P<0.001),preference for cold drinks(OR=51.505,95%CI:9.66～274.76,P<0.001),parents eating out frequently were the risk factors(OR=1.933,95%CI:1.13～3.30,P=0.016),and hand washing before eating and after defecation(OR=0.314,95%CI:0.13～0.76,P=0.011)was the protective factor.The age correlation coefficient was positive and the infection rate increased with age.Conclusion: The infection rate of Hp in preschool children in Baise Youjiang District was high,and there was no gender or ethnic difference,but the infection rate increased gradually with age.Hp infection in children is associated with Hp infection in parents.Finger sucking and toy sucking,preference for cold drinks,and parents eating out frequently were risk factors.Washing hands before eating and after defecation was a protective factor.Strengthening children’s hand hygiene and oral hygiene,guiding children’s healthy diet,popularizing chopsticks hygiene and meal separation system are of great significance for preventing children from infection with Hp. |
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