| Objective: To observe the clinical efficacy of Jiawei Shenlingbaizhu Powder and acupoint catgut embedding combined with western medicine seretide in the treatment of patients with chronic persistent bronchial asthma with deficiency of both lung and spleen,and to compare the pulmonary function at 1 day before treatment and at 1 month and 3 months after treatment Indicators,inflammation-related indicators,exhaled nitric oxide(FeNO),asthma control test(ACT)score,TCM syndrome score,relieving drug use during treatment,and recurrence,providing theoretical basis for TCM treatment of bronchial asthma,and clinical treatment of bronchus New ideas for developing asthma.Methods: This study collected 80 patients who met the inclusion criteria in the outpatient and ward of the Pulmonary Department of Qinhuangdao Hospital of Traditional Chinese Medicine from January 2019 to July 2020.They were randomly divided into control group(40 cases)and treatment group(40 cases).The control group was given salmeterol ticasone powder(seretide)inhalation treatment.On the basis of the treatment of the control group,the treatment group was given Jiawei Shenlingbaizhu powder combined with acupoint embedding therapy.One month is a course of treatment,and both groups have 3 courses of treatment.The lung function indexes before and after treatment,nitric oxide detection(FeNO),asthma control test(ACT)score,TCM syndrome score,emergency plan use,and recurrence were compared between the two groups before and after treatment.At the same time,shedding and adverse events were recorded.Use software SPSS23.0 for statistical data analysis and evaluation of curative effect.Results:(1)Comparison of pulmonary function indexes(FEV1%,PEF): Comparison of pulmonary function(FEV1%,PEF)levels between the two groups before and after treatment showed significant statistical differences(P<0.01);after treatment,there was a statistical difference between the two groups Significant(P<0.01).(2)Comparison of inflammation-related indicators(FeNO): The FeNO levels of the two groups before and after treatment were significantly different(P<0.01);after the treatment,there was a statistically significant difference between the two groups(P<0.01).(3)Comparison of Asthma Control Test(ACT)scores: The comparison of ACT scores between the two groups before and after treatment was statistically significant(P<0.01);the comparison between the two groups after treatment was statistically significant(P<0.01).(4)Comparison of TCM syndrome scores: Comparison of total curative effect: The total effective rate of the control group was 76.92%,and the total effective rate of the treatment group was 97.37%.There was a significant statistical difference between the two groups(P<0.01).After treatment,the scores of abdominal distension,loose stools,fatigue and fatigue symptoms in the control group were significantly different from those before treatment(P<0.05),and the scores of wheezing,shortness of breath,cough,sputum,wheezing,spontaneous sweating and sticky symptoms were higher than those before treatment.Significant statistical difference(P<0.01);all symptoms in the treatment group were significantly different from those before treatment(P<0.01).After treatment,there was no statistical difference in the scores of wheezing,sputum,and wheezing between the two groups(P>0.05).There was a statistical difference in the scores of cough symptoms(P<0.05),abdominal distension,loose stools,spontaneous sweating,fatigue and fatigue There was a significant statistical difference in the symptom score(P<0.01).(5)Comparison of the use of emergency plans: There was a statistical difference in the number of patients using emergency plans during the treatment period between the two groups(P<0.05).(6)Comparison of recurrence rate: There was a statistical difference in the recurrence rate of the two groups at 3 months after the end of treatment(P<0.05).(7)Safety comparison: The safety indexes of the two groups of patients before and after treatment were all within the normal range,and there was no obvious abnormality.Conclusion: Jiawei Shenlingbaizhu powder combined with acupoint embedding can effectively reduce the TCM syndrome scores of patients with lung and spleen deficiency type bronchial asthma in chronic persistent period,improve lung function,reduce airway inflammation,improve asthma control,and improve clinical symptoms.Reduce the recurrence rate and reduce the acute attack;the treatment process showed good safety,no serious adverse reactions were seen,and it is worthy of popularization and application. |
