Research On TCM Syndrome Regularity Of Mixed Anxiety-depressive Disorder Based On Data Mining Technology

Objectives:In previous literature research foundation,proposed by the way of questionnaire survey to mixed anxiety and depression disorder patients for cross-sectional study.This article reseach the TCM syndrome type distribution law of MADD by cluster analysis and association rules,conclude the pathogenesis of MADD,aiming to lay a foundation for the treatment of the disease.Methods:Combined early literature research and consultation,formulate by patients generally material,demographic data and the clinical symptoms related to the main contents of the clinical information collection table.Cross-sectional design of clinical epidemiological methods,to Chaoyang District Asian Sports Village community and Chaoyang District Xiaoguan community MADD patients in June 2015-March 2016.Establish a database and use descriptive analysis,clustering analysis and statistical methods of data analysis,discusses the TCM syndrome types of MADD.Result:The survey of 208 cases of patients with MADD common symptoms,frequency in the top 20 include anxiety(93.30%),amnesia(92.80%),upset irritability(92.3%),fatigue(90.4%),intension(88.5%),sad and sentimental(88.5%),backache(83.7%),inattention(79.8%),dreaminess(79.8%),Droopy(77.4%),palpitation(76.9%),fear(75.0%),suspire(75.0%),imidity(74.0%),depression(73.2%),lack of interest(73.1%),feel restless(71.2%),difficulty falling asleep(70.2%),dry mouth tastes bitter(69.2%),dyspnea chest discomfort(69.2%).These TCM symptoms mostly cover the main symptoms of MADD.By using association rules analysis TCM symptoms of 208 patients in MADD,extract eight syndrome factors included gallbladder qi deficiency,heart blood deficiency,liver fire hyperactivity,kidney yang deficiency,phlegm,spleen qi deficiency,liver qi depression,yin deficiency.And conclude three kinds of common types,named cardiac-gallbladder qi deficiency,spleen-kidney yang deficiency and hepatopyrexia.Cardiac-gallbladder qi deficiency in the 208 cases accounted for 46.1 percent,spleen-kidney yang deficiency accounted for 20.7 percent,and hepatopyrexia accounted for 27.4 percent.The main symptoms of cardiac-gallbladder qi deficiency are palpitation,anxiety,fear,timidity,depression,droopy,suspicious,amnesia,dreaminess,fatigue.Minor symptoms are intension,upset irritability,feel restless,sad and sentimental,lack ofinterest,inattention,difficulty falling asleep,early-wake,dizziness.Main symptoms ofspleen-kidney yang deficiency are anxiety,timidity,sad and sentimental,depression,droopy,inattention,fatigue,amnesia,poor appetite,tasteless,tinnitus,chilly and cold.Minor symptoms are lack of interest,feel restless,suspicious,dreaminess,headache,dizziness,belching,abdominal distension,diarrhea,limp feet and knees,backache,frequent urination,hyposexuality,ED,prospermia.Main symptoms of hepatopyrexia are anxiety,fear,intension,upset irritability,lack of interest,amnesia,sigh,distending pain in hypochondrium,thirsty and bitter taste,dry eyes,tinnitus.Minor symptoms are feel restless,sad and sentimental,depression,inattention,suspicious,dreaminess,headache,dizziness,spontaneos sweating,irregular menstruation,abdominal distension,breast distending pain,difficulty falling asleep,early-wake.Conclusion:First,this survey throug cross-sectional design to 208 cases of MADD patients.By researching TCM symptoms of MADD,statistics the freqency of every symptom,and the symptoms in high freqency are mostly covers MADD main symptoms.Second,using cluster analysis and association rules discover the distribution regularity of TCM syndrome types,this study conclude three common TCM syndrome types of mixed anxiety depression disorder,named cardiac-gallbladder qi deficiency,spleen-kidney yang deficiency and hepatopyrexia.