Clinical Observation On The Effect Of Huxinkang Tablet On Hcy And Hs-CRP In Patients With Microvascular Angina Pectoris (Qi Deficiency, Phlegm And Blood Stasis Syndrome)

Objective: Through the observation of randomized controlled trials,this paper discusses the curative effect of Huxinkang tablets in the treatment of patients with microvascular angina pectoris of qi deficiency and phlegm stasis syndrome,discusses its influence on serum Hcy and hs CRP,and further discusses the safety and mechanism of Huxinkang tablets in the treatment of microvascular angina pectoris,so as to provide basis for further clinical application.Methods:According to the random number table method,60 hospitalized patients with microvascular angina pectoris of qi deficiency and phlegm stasis syndrome were divided into treatment group and control group,30 cases in each group.The control group was treated with conventional western medicine,and the treatment group was treated with Huxinkang tablets on the basis of the conventional western medicine.The course of treatment was 4 weeks.The clinical efficacy,ECG efficacy,angina pectoris efficacy,TCM syndrome efficacy,serum Hcy,hs CRP and other indicators were observed before and after treatment.Results:(1)Comparison of clinical efficacy: the total effective rate of the treatment group was 93.3%,and that of the control group was 76.7%,the difference between the two groups was statistically significant(P < 0.05);(2)comparison of ECG efficacy: the total effective rate of the treatment group was 80.0%,and that of the control group was 56.7%,the difference between the two groups was statistically significant(P< 0.05))(3)angina pectoris curative effect comparison;the total effective rate of the treatment group was90.0%,the control group was 60.0%,the difference between the two groups was statistically significant(P< 0.05);(4)nitroglycerin reduction comparison: the total effective rate of the treatment group was 90.0%,the control group was 63.3%,the difference between the two groups was statistically significant(P< 0.05);(5)TCM syndrome curative effect comparison: the total effective rate of the treatment group was 93.3%,the control group was 73.3%(6)comparison of serum Hcy and hs CRP: after treatment,the serum Hcy and hs CRP levels of the two groups were decreased,and the difference between the two groups was statistically significant(P< 0.05),The level of hs CRP in the treatment group was significantly better than that in the control group,the difference was statistically significant(P< 0.05);(7)drug safety: before and after treatment,the blood routine,electrolyte,liver and kidney function of the two groups did not change significantly,and there was no serious adverse reaction during the treatment,the comparison between the two groups and within the group was not statistically significant(P > 0.05),the safety of the two drugs was better.Conclusion:1.Baoxinkang tablet can effectively improve the clinical symptoms,ECG,angina pectoris and the utilization rate of nitroglycerin in patients with microvascular heart pattern pain,Qi deficiency,phlegm and stasis mutual obstruction syndrome,and significantly reduce the Hcy and hs CRP levels of patients.2.the combination of Baoxinkang tablet and Western medicine has a definite effect and safety in the treatment of qi deficiency and blood stasis mutual obstruction syndrome of microvascular angina pectoris,which is worth clinical application and further research...